Ignite Creation Date:
2024-05-05 @ 12:02 PM
Last Modification Date:
2024-10-26 @ 9:19 AM
Study NCT ID:
NCT00222898
Status:
COMPLETED
Last Update Posted:
2007-02-19
First Post:
2005-09-20
Brief Title:
Cancer Detection in Pancreatic Cysts
Sponsor:
University of Pittsburgh
Organization:
University of Pittsburgh
Study Overview
Official Title:
Pancreatic Cyst DNA Analysis
Status:
COMPLETED
Status Verified Date:
2007-02
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
The purpose of this study is to assist with early and accurate diagnosis of cancer in pancreatic cysts based on the analysis of DNA obtained by endoscopic ultrasound guided fine needle aspiration
Detailed Description:
The study of pancreatic diseases is hindered by the organs deep seated location and especially lack of symptoms during the early stages of disease development and progression eg pancreatic cancer This is particularly true of pancreatic cysts the variety and the malignant potential of which encompass a broad spectrum The radiological features distinguishing a benign from a pre-malignant to a frankly malignant cyst in the pancreas are frequently underwhelming and have lead to the clinical practice of sampling all but the most obvious The yield of the aspirate in turn is frequently not of a quality upon which a clinical decision can be based
Most would agree that the best approach for management of pancreatic cystic neoplasm lies in early diagnosis ideally at a precancerous stage The effectiveness and applicability of this study is the based on the ability of the cyst DNA analysis to stratify the patients at risk of developing pancreatic cancer based on the extent of accumulated mutational damage
Most would agree that the best approach for management of pancreatic cystic neoplasm lies in early diagnosis ideally at a precancerous stage The effectiveness and applicability of this study is the based on the ability of the cyst DNA analysis to stratify the patients at risk of developing pancreatic cancer based on the extent of accumulated mutational damage
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None