Ignite Creation Date:
2024-05-05 @ 12:02 PM
Last Modification Date:
2024-10-26 @ 9:19 AM
Study NCT ID:
NCT00229528
Status:
COMPLETED
Last Update Posted:
2008-09-22
First Post:
2005-09-27
Brief Title:
Effect of Paroxetine on COAT-Platelet Production in Normal Volunteers and Patients With Cardiovascular Disease
Sponsor:
University of Oklahoma
Organization:
University of Oklahoma
Study Overview
Official Title:
Dose Ranging Study of the Effect of Paroxetine on COAT-Platelet Production in Normal Volunteers and Patients With Cardiovascular Disease
Status:
COMPLETED
Status Verified Date:
2008-09
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
COAT-platelets stands for collagen and thrombin stimulated platelets which are two things in the body that make platelets stick together These platelets may be important in the initiation of a heart attack myocardial infarction A chemical in the body called serotonin maybe responsible for COAT-platelet production Paroxetine causes a significant reduction in platelet serotonin and therefore may have value in preventing heart attacks Therefore the current study is designed to determine whether paroxetine will decrease COAT-platelet production in normal volunteers and patients with cardiovascular disease
Detailed Description:
None
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None