Ignite Creation Date:
2024-05-05 @ 12:02 PM
Last Modification Date:
2024-10-26 @ 9:19 AM
Study NCT ID:
NCT00224926
Status:
COMPLETED
Last Update Posted:
2011-09-19
First Post:
2005-09-21
Brief Title:
The Natural Course of Trichophyton Tonsurans Carriage and Infection A Molecular and Biochemical Evaluation
Sponsor:
Childrens Mercy Hospital Kansas City
Organization:
Childrens Mercy Hospital Kansas City
Study Overview
Official Title:
The Natural Course of Trichophyton Tonsurans Carriage and Infection A Molecular and Biochemical Evaluation
Status:
COMPLETED
Status Verified Date:
2011-09
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
To explore carrier and infection status of Ttonsurans tinea capitis and characterize the host-pathogen interaction as it relates to the disease presentation The general hypothesis for this study is as follows the type of genotypic and phenotypic variant to which a child is exposed accounts for the presentation status observed in Trichophyton tonsurans infectionThe global outcome of this investigation is to reveal potential new drug targets designed to improve treatment outcomes in these children
Detailed Description:
Tinea capitis is an overwhelmingly prevalent disease of childhood estimated to be present in approximately 1 in 20 children at any point in time with an equal number of children serving as carriers of the fungal pathogen Despite the widespread nature of the disease the natural course of the infection remains incompletely described The study will be driven by the following hypothesis the type of genotypic and phenotypic variant to which a child is exposed accounts for the presentation status observed in Trichophyton tonsurans infection
A fungal scalp culture will be acquired from all participants using a brush culture technique Samples will be collected once a month over a two year time period
A fungal scalp culture will be acquired from all participants using a brush culture technique Samples will be collected once a month over a two year time period
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None