Ignite Creation Date:
2024-05-05 @ 10:23 AM
Last Modification Date:
2024-10-26 @ 9:02 AM
Study NCT ID:
NCT00002144
Status:
COMPLETED
Last Update Posted:
2005-06-24
First Post:
1999-11-02
Brief Title:
The Pilot Study of Foscarnet Cream in the Treatment of Mucocutaneous Herpes Simplex Virus Infections in Immunocompromised Patients Unresponsive to Acyclovir Treatment
Sponsor:
Astra USA
Organization:
NIH AIDS Clinical Trials Information Service
Study Overview
Official Title:
The Pilot Study of Foscarnet Cream in the Treatment of Mucocutaneous Herpes Simplex Virus Infections in Immunocompromised Patients Unresponsive to Acyclovir Treatment
Status:
COMPLETED
Status Verified Date:
1996-03
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
PRIMARY To evaluate the clinical activity of foscarnet cream on the index lesion of mucocutaneous herpes simplex virus HSV infections in immunocompromised patients previously unresponsive to acyclovir treatment
SECONDARY To evaluate the clinical activity and virologic activity of foscarnet cream on all treated lesions in this patient population To evaluate the local tolerance and side effects of treatment with foscarnet cream in this patient population
SECONDARY To evaluate the clinical activity and virologic activity of foscarnet cream on all treated lesions in this patient population To evaluate the local tolerance and side effects of treatment with foscarnet cream in this patient population
Detailed Description:
Patients receive topical applications of one percent foscarnet cream five times daily for up to 6 weeks those who show no evidence of epithelialization of the index lesion after 3 or more weeks are removed from study and offered intravenous foscarnet Patients who show a good response to topical foscarnet cream at the end of 6 weeks may continue receiving treatment at the discretion of the investigator
Study Oversight
Has Oversight DMC:
Is a FDA Regulated Drug?:
Is a FDA Regulated Device?:
Is an Unapproved Device?:
Is a PPSD?:
Is a US Export?:
Is an FDA AA801 Violation?:
Secondary IDs
| Secondary ID | Type | Domain | Link |
|---|---|---|---|
| 92-FT-57 | None | None | None |