Ignite Creation Date:
2024-05-05 @ 10:23 AM
Last Modification Date:
2024-10-26 @ 9:05 AM
Study NCT ID:
NCT00006500
Status:
COMPLETED
Last Update Posted:
2016-06-24
First Post:
2000-11-16
Brief Title:
Trends in Trans-Fatty Acid Intake Between 1980 and 1997
Sponsor:
University of Minnesota
Organization:
University of Minnesota
Study Overview
Official Title:
None
Status:
COMPLETED
Status Verified Date:
2016-06
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
To examine trends in trans-fatty acid intake by using newly available nutrient data to recalculate 24 dietary recalls from the Minnesota Heart Survey
Detailed Description:
BACKGROUND
In recent years concern has arisen about the potential health hazards of trans-fatty acids in the American diet Dietary intake of trans-fatty acids has been linked to unhealthy shifts in serum lipid profiles and to coronary heart disease CHD in a number of studies Although several studies have estimated intakes of trans-fatty acids in US populations presently data is lacking regarding trends in intake of trans-fatty acids in the population Furthermore it is unclear how trends in intake of trans-fatty acids may be related to changes in other dietary and non-dietary CHD risk factors and CHD mortality
DESIGN NARRATIVE
The study used newly available nutrient data to recalculate dietary data collected as part of the Minnesota Heart Survey MHS to examine trends in intake of trans-fatty acids The MHS was an ongoing observational epidemiologic study of trends in risk factors and cardiovascular morbidity and mortality among independent cross-sectional probability samples of the Minneapolis-St Paul Minnesota metropolitan area Surveys were conducted in 1980-1982 1985-1987 1990-1992 and 1995-1997 Diet was among the CVD risk factors measured as part of each survey In this research 24-hour dietary recalls collected from MHS participants were recalculated using an updated food and nutrient database that included trans-fatty acid values 161 181 182 and total Intake estimates resulting from recalculation were analyzed to examine temporal trends in trans-fatty acid intake between 1980 and 1997 and to examine the relationship of temporal trends in trans-fatty acid intake to temporal changes in other dietary and non-dietary CHD risk factors and changes in CHD mortality The MHS data provided a unique opportunity to examine a dietary constituent only recently recognized as a potential risk factor for CHD
In recent years concern has arisen about the potential health hazards of trans-fatty acids in the American diet Dietary intake of trans-fatty acids has been linked to unhealthy shifts in serum lipid profiles and to coronary heart disease CHD in a number of studies Although several studies have estimated intakes of trans-fatty acids in US populations presently data is lacking regarding trends in intake of trans-fatty acids in the population Furthermore it is unclear how trends in intake of trans-fatty acids may be related to changes in other dietary and non-dietary CHD risk factors and CHD mortality
DESIGN NARRATIVE
The study used newly available nutrient data to recalculate dietary data collected as part of the Minnesota Heart Survey MHS to examine trends in intake of trans-fatty acids The MHS was an ongoing observational epidemiologic study of trends in risk factors and cardiovascular morbidity and mortality among independent cross-sectional probability samples of the Minneapolis-St Paul Minnesota metropolitan area Surveys were conducted in 1980-1982 1985-1987 1990-1992 and 1995-1997 Diet was among the CVD risk factors measured as part of each survey In this research 24-hour dietary recalls collected from MHS participants were recalculated using an updated food and nutrient database that included trans-fatty acid values 161 181 182 and total Intake estimates resulting from recalculation were analyzed to examine temporal trends in trans-fatty acid intake between 1980 and 1997 and to examine the relationship of temporal trends in trans-fatty acid intake to temporal changes in other dietary and non-dietary CHD risk factors and changes in CHD mortality The MHS data provided a unique opportunity to examine a dietary constituent only recently recognized as a potential risk factor for CHD
Study Oversight
Has Oversight DMC:
Is a FDA Regulated Drug?:
Is a FDA Regulated Device?:
Is an Unapproved Device?:
Is a PPSD?:
Is a US Export?:
Is an FDA AA801 Violation?:
Secondary IDs
| Secondary ID | Type | Domain | Link |
|---|---|---|---|
| R03HL064592 | NIH | None | httpsreporternihgovquickSearchR03HL064592 |