Ignite Creation Date:
2024-05-05 @ 12:07 PM
Last Modification Date:
2024-10-26 @ 9:20 AM
Study NCT ID:
NCT00244400
Status:
COMPLETED
Last Update Posted:
2006-10-17
First Post:
2005-10-25
Brief Title:
Examine the Possible Association of Hepatic CYP3A Activity and the Susceptibility to Femur Head Necrosis
Sponsor:
Osaka City University
Organization:
Osaka City University
Study Overview
Official Title:
None
Status:
COMPLETED
Status Verified Date:
2006-10
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
The purpose of the present study was to examine the possible association of hepatic CYP3A activity and the susceptibility to femur head necrosis in patients treated with corticosteroids
Detailed Description:
Femur head necrosis is one of the major side effects of corticosteroid therapy Since corticosteroids are metabolized by hepatic cytochrome P-450 CYP 3A a low endogenous activity of this enzyme may contribute to the pathogenesis of ONFH The purpose of the present study was to examine the possible association of hepatic CYP3A activity and the susceptibility to femur head necrosis in patients treated with corticosteroids
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None