Ignite Creation Date:
2024-05-05 @ 12:08 PM
Last Modification Date:
2024-10-26 @ 9:21 AM
Study NCT ID:
NCT00256802
Status:
COMPLETED
Last Update Posted:
2009-04-01
First Post:
2005-11-21
Brief Title:
The Diameter of the Middle Cerebral Artery Measured With Magnetic Resonance Angiography
Sponsor:
Danish Headache Center
Organization:
Danish Headache Center
Study Overview
Official Title:
The Diameter of the Middle Cerebral Artery Measured With Magnetic Resonance Angiography MRA Under Provocation With Glyceryl Trinitrate in Healthy Volunteers
Status:
COMPLETED
Status Verified Date:
2004-05
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
To examine the ability of MRA to measure the effect of GTN on the intra-cranial vascular response during the GTN-induced headache in healthy volunteers
Detailed Description:
The only intra cranial structures innervated by sensory nerves and therefore a possible source of the headpain are the meninges and the large intracerebral arteries The dilatation of the cerebral vessels may not be the origin of the head pain per se but measurements of the intra cerebral vascular bed in the past has proven valuable in the migraine-research and has helped elucidate the basis for the migraine aura Olesen Friberg et al 1990 The effects of different signal molecules on the intra cerebral vasculature continue to be an important field in the migraine research in the search for possible pain causing signaling molecules
Therefore we have set up at study to examine if MR-Angiography MRA can be used for monitoring of the vascular response after challenge with the known vasodilator GTN This drug was chosen because it is well characterized and a large body of evidence from earlier studies could serve as background data Thomsen 1997
Therefore we have set up at study to examine if MR-Angiography MRA can be used for monitoring of the vascular response after challenge with the known vasodilator GTN This drug was chosen because it is well characterized and a large body of evidence from earlier studies could serve as background data Thomsen 1997
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None