Ignite Creation Date:
2024-05-06 @ 9:49 AM
Last Modification Date:
2024-10-26 @ 12:20 PM
Study NCT ID:
NCT03089892
Status:
COMPLETED
Last Update Posted:
2024-07-05
First Post:
2017-03-20
Brief Title:
A Perspective Study of Cancer-related Fatigue in Gynecologic Cancer Patients Under Chemotherapy
Sponsor:
Tri-Service General Hospital
Organization:
Tri-Service General Hospital
Study Overview
Official Title:
A Perspective Study of Cancer-related Fatigue in Gynecologic Cancer Patients Under Chemotherapy
Status:
COMPLETED
Status Verified Date:
2024-07
Last Known Status:
Recruiting
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
Chemotherapy is effective and most often used to treat cancer The common drugs used on gynecologic cancer treatment include platinum compounds like cisplatin and carboplatin which combined with taxane topotecan or liposomal doxorubicin to date The most side effects of chemotherapy are esophagitis mucositis anxiety nausea vomiting abdominal convulsion painful swallowing fatigue and sometimes diarrhea dizziness allergy rash itching neutropenia thrombocytopenia fever chills cough pain anemia and bleeding
Cancer-related fatigue CRF an indicator of quality of life is a highly prevalent symptom 75-80 during treatment and in patients with advanced cancer yet is sometimes ignored Fatigue affected their life more than pain Proposed criteria for CRF have been adopted for inclusion in the International Statistical Classification of Disease and Related Health Problems Tenth Revision Clinical Modification ICD-10-CM Therefore more in-depth researches on CRF are needed in Taiwan Patients with CRF in need of improvement commonly use nutrition supplements acupuncture healthy food massage drugs etc Hence patients with CRF could consult their vital physician for an appropriate treatment Furthermore several drugs could be chosen to relieve CRF including anemia drugs antipsychotics or Astragalus polysaccharides extract
The objective of this retrospective study is to collect and analyze the medical records of gynecologic cancer patients who who had received chemotherapy with or without prescription drug treatment for cancer-related fatigue in the Department of Obstetrics Gynecology of Tri-Service General Hospital This study will compare the fatigue improvement profile by different chemotherapy regimens tumor stage CRF treatment etc and investigate the association between the profile of fatigue improvement and fatigue cluster weight loss and other symptoms of functional assessment of cancer therapy This study will also collect blood specimens and analyze the correlation of the cytokine profile andor immune profileThese results will supply physicians with more understanding about CRF and help them to enhance the quality on gynecologic cancer care to being perfected in the future
Cancer-related fatigue CRF an indicator of quality of life is a highly prevalent symptom 75-80 during treatment and in patients with advanced cancer yet is sometimes ignored Fatigue affected their life more than pain Proposed criteria for CRF have been adopted for inclusion in the International Statistical Classification of Disease and Related Health Problems Tenth Revision Clinical Modification ICD-10-CM Therefore more in-depth researches on CRF are needed in Taiwan Patients with CRF in need of improvement commonly use nutrition supplements acupuncture healthy food massage drugs etc Hence patients with CRF could consult their vital physician for an appropriate treatment Furthermore several drugs could be chosen to relieve CRF including anemia drugs antipsychotics or Astragalus polysaccharides extract
The objective of this retrospective study is to collect and analyze the medical records of gynecologic cancer patients who who had received chemotherapy with or without prescription drug treatment for cancer-related fatigue in the Department of Obstetrics Gynecology of Tri-Service General Hospital This study will compare the fatigue improvement profile by different chemotherapy regimens tumor stage CRF treatment etc and investigate the association between the profile of fatigue improvement and fatigue cluster weight loss and other symptoms of functional assessment of cancer therapy This study will also collect blood specimens and analyze the correlation of the cytokine profile andor immune profileThese results will supply physicians with more understanding about CRF and help them to enhance the quality on gynecologic cancer care to being perfected in the future
Detailed Description:
About 60 gynecologic cancer patients medical records are expected to collect and analyze in this retrospective study The data collection from medical records of gynecologic cancer patients who had received chemotherapy with or without prescription drug treatment for cancer-related fatigue include the demographic information eg height weight age sex tumor stage time from tumor diagnoses prescription drug of cancer-related fatigue treatment and chemotherapy toxicities the diagnosis and severity of cancer-related fatigue functional assessment of cancer therapy and so on
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None