Ignite Creation Date:
2024-05-05 @ 12:09 PM
Last Modification Date:
2024-10-26 @ 9:21 AM
Study NCT ID:
NCT00269633
Status:
COMPLETED
Last Update Posted:
2016-03-28
First Post:
2005-12-22
Brief Title:
Research Study of Treatment for Winter Depression With Different Colors of Light
Sponsor:
Thomas Jefferson University
Organization:
Thomas Jefferson University
Study Overview
Official Title:
Optimizing Light Wavelength for Treatment of Seasonal Affective Disorder
Status:
COMPLETED
Status Verified Date:
2016-03
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
The specific aim of this study is to test the hypothesis that light stimuli concentrated around 467 nm will evoke a significantly stronger therapeutic response in SAD patients compared to light stimuli concentrated around 657 nm at an equal photon density
The secondary objective of this study is to determine the efficacy of different colors and levels of light in order to optimize therapeutic benefit while also minimizing side effects and maintaining safety of light exposure
The secondary objective of this study is to determine the efficacy of different colors and levels of light in order to optimize therapeutic benefit while also minimizing side effects and maintaining safety of light exposure
Detailed Description:
Studies report as many as 1 out of every 5 Americans is affected by mild to severe Seasonal Affective Disorder SAD winter depression Although the exact cause of this condition is unknown bright light has proven to be an effective therapeutic treatment for many people with SAD The light sources that have been traditionally used for treatment of SAD produce white light with great variability in the balance of wavelengths that are emitted across the visible spectrum Although several studies have attempted to test the effectiveness of different wavelengths for treatment of SAD the devices used in those studies employed broad bandwidths of light With the technological advancements in light emitting diodes LEDs the production of new light therapy equipment with much narrower bandwidths of light is possible Side effects of exposure to traditional white light therapy for SAD have included hypomanic activation irritability headache eyestrain and nausea We hypothesize that when the wavelength of light therapy is optimized it should be feasible to elicit strong therapeutic benefits with lower light intensities and fewer side effects Previous studies approved by the Jefferson IRB and successfully completed by our laboratory have shown that some colors of light are more effective in treating SAD than other colors
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None