Ignite Creation Date:
2024-05-05 @ 12:10 PM
Last Modification Date:
2024-10-26 @ 9:21 AM
Study NCT ID:
NCT00267813
Status:
COMPLETED
Last Update Posted:
2008-05-07
First Post:
2005-12-20
Brief Title:
The Effects of Craving and Abstinence From Cigarettes on Brain Metabolism in Smokers
Sponsor:
Tel-Aviv Sourasky Medical Center
Organization:
Tel-Aviv Sourasky Medical Center
Study Overview
Official Title:
The Effects of Craving and Abstinence From Cigarettes on Brain Metabolism in Smokers
Status:
COMPLETED
Status Verified Date:
2008-05
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
Craving and withdrawal from smoking cigarettes are major factors for relapse We investigated craving for cigarettes in smokers undergoing pharmacological treatment with Bupropion Zyban We compare cue-induced reactivity to smoking videos in smokers who were successfully treated with Bupropion to smokers who are still smoking We measured the brains metabolic activity in response to smoking and neutral cues in Positron Emission Tomography using FDG
Detailed Description:
Craving and withdrawal from smoking cigarettes are major factors for relapse We investigated craving for cigarettes in smokers undergoing pharmacological treatment with Bupropion Zybanfor 2 months We compare cue-induced reactivity to smoking videos in smokers who were successfully treated with Bupropion to smokers who are still smoking We measured the brains metabolic activity after exposure to videotapes showing smoking and neutral scenes in Positron Emission Tomography using FDG There were 2 scanning sessions one with a smoking videotape and one with a neutral video separated by a week So far we have compared the brains metabolic activity in 6 abstinent smokers and 6 still smokers
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None