Ignite Creation Date:
2024-05-05 @ 12:11 PM
Last Modification Date:
2024-10-26 @ 9:21 AM
Study NCT ID:
NCT00260533
Status:
COMPLETED
Last Update Posted:
2016-06-24
First Post:
2005-11-29
Brief Title:
Efficacy and Tolerability of Atomoxetine Strattera in Adult Patients With Generalized Social Anxiety Disorder
Sponsor:
University of California San Diego
Organization:
University of California San Diego
Study Overview
Official Title:
Double Blind Placebo Controlled Parallel Group Comparison of Atomoxetine Strattera for Generalized Social Anxiety Disorder GSAD
Status:
COMPLETED
Status Verified Date:
2016-05
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
The purpose of this study is to determine the effectiveness and tolerability of atomoxetine Strattera in adult patients with generalized social anxiety disorder an anxiety disorder characterized by a fear of interpersonal interactions
Detailed Description:
Controlled studies show that approximately 50 of patients with generalized social anxiety disorderGSADwill respond to treatment with available pharmacotherapeutic agents such as SSRIs This still leaves 50 that respond partially or not at all Those who do respond often experience adverse events eg sexual dysfunction which leads them to discontinue treatment Thus there is a strong rational for identifying alternatives to SSRIs that are effective with fewer side effects or with a different side-effect profile that features less sexual dysfunctionfor the treatment of GSAD Available data demonstrate that sustained-release venlafaxine a dual reuptake inhibitor is also effective for GSADStein et al 2005 It is unclear from these studies whether serotonin reuptake is integral to efficacy for social anxiety disorder or whether norepinephrine reuptake will convey similar efficacy Atomoxetine Stratteraan inhibitor of the presynaptic norepinephrine transporter is an ideal candidate to address both these issues
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None