Ignite Creation Date:
2024-05-05 @ 12:11 PM
Last Modification Date:
2024-10-26 @ 9:21 AM
Study NCT ID:
NCT00267982
Status:
TERMINATED
Last Update Posted:
2011-07-06
First Post:
2005-12-20
Brief Title:
Radiofrequency Ablation of Ectopic Atrial Tachycardia
Sponsor:
Childrens Healthcare of Atlanta
Organization:
Childrens Healthcare of Atlanta
Study Overview
Official Title:
A Retrospective Review of Outcomes Related to Radiofrequency Ablation of Ectopic Atrial Tachycardia
Status:
TERMINATED
Status Verified Date:
2011-06
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
significant conclusive data has been collected
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
A retrospective chart review will be performed on 50 patients who received RFA for the treatment of EAT between August 1992 and August 2003 at Childrens Healthcare of Atlanta
The use of the CARTOBiosense catheter has improved outcomes with decreased radiation exposure to patients
The use of the CARTOBiosense catheter has improved outcomes with decreased radiation exposure to patients
Detailed Description:
Ectopic Atrial Tachycardia EAT is a relatively rare arrhythmia in the pediatric population It is defined by a run of more than 3 premature atrial contractions together In EAT the arrhythmia tends to increase in rate over a period of time and then slows down gradually to a normal rhythm Ectopic Atrial Tachycardia EAT is mostly encountered in patients with structurally normal hearts however occasionally physicians do observe this type of disorder in children following surgery for congenital heart defects Current reports suggest that EAT occurs in approximately 1 in 10000 children Hamilton 2002
Children with EAT usually present with a multitude of symptoms The most common symptoms associated with pediatric EAT are palpitations chest pain lightheadedness presyncope and dyspnea Other symptoms can include exercise intolerance and congestive heart failure These are usually late manifestations In the patients with tachycardia induced CM the time of development of CM is dependent on the rate and duration of the tachycardia however in most cases dilation is present upon diagnosis This CM can be reversed with successful treatment of the arrhythmia
The treatment for chronic EAT includes medications such as adenosine and for difficult to control cases Radiofrequency Ablation RFA RF ablation has been successful in curing EAT with success rates ranging from 75-100 It has been shown that the complication rates are similar to other RF ablation procedures with a higher risk of recurrence Hamilton 2002
At Childrens Healthcare of Atlanta the cardiac catheterization lab performs approximately 10 Radiofrequency ablations for EAT each year The goal of this retrospective review is to assess the frequency of recurrence of the EAT among a subset of patients receiving treatment between August 1992 - August 2003
Children with EAT usually present with a multitude of symptoms The most common symptoms associated with pediatric EAT are palpitations chest pain lightheadedness presyncope and dyspnea Other symptoms can include exercise intolerance and congestive heart failure These are usually late manifestations In the patients with tachycardia induced CM the time of development of CM is dependent on the rate and duration of the tachycardia however in most cases dilation is present upon diagnosis This CM can be reversed with successful treatment of the arrhythmia
The treatment for chronic EAT includes medications such as adenosine and for difficult to control cases Radiofrequency Ablation RFA RF ablation has been successful in curing EAT with success rates ranging from 75-100 It has been shown that the complication rates are similar to other RF ablation procedures with a higher risk of recurrence Hamilton 2002
At Childrens Healthcare of Atlanta the cardiac catheterization lab performs approximately 10 Radiofrequency ablations for EAT each year The goal of this retrospective review is to assess the frequency of recurrence of the EAT among a subset of patients receiving treatment between August 1992 - August 2003
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None