Ignite Creation Date:
2024-05-06 @ 10:18 AM
Last Modification Date:
2024-10-26 @ 12:27 PM
Study NCT ID:
NCT03212560
Status:
COMPLETED
Last Update Posted:
2019-02-15
First Post:
2017-07-03
Brief Title:
Exercise Capacity and Physical Activity Levels in Newly Diagnosed Hematologic Malignant Patients
Sponsor:
Gazi University
Organization:
Gazi University
Study Overview
Official Title:
Exercise Capacity Physical Activity Level and Quality of Life in Newly Diagnosed Hematologic Malignant Patients
Status:
COMPLETED
Status Verified Date:
2019-02
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
Hematologic malignancies are neoplasms that affect the blood bone marrow and lymph nodes Hematological malignancies are the most common forms of leukemia lymphoma and myeloma with numerous subtypes The general symptoms of leukemia are fatigue increased susceptibility to infection bleeding and the formation of bruises easily Typical lymphoma symptoms are night sweats and involuntary weight loss recurrent fever fatigue and itching Myeloma patients often have bone pain fatigue anemia hypercalcemia or infection symptoms
Adverse effects of hematologic malignancies and treatments cause abnormality in physical function and quality of life Treatments such as chemotherapy radiotherapy and hematopoietic stem cell transplantation which may have side effects on the body systems are used in early or late period The most common side effect due to chemotherapy is fatigue Vomiting weight loss anemia depression decreased aerobic capacity loss of muscle strength decreased physical functioning and deterioration in the quality of life are indirect side effects seen in patients
In the literature side effects of hematological malignancies have been investigated after treatment in patients However no study investigated exercise capacity quality of life physical activity level and pulmonary functions on newly diagnosed hematologic malignant patients Therefore the investigators aimed to compare aforementioned outcomes in newly diagnosed hematologic malignant patients and healthy controls
Adverse effects of hematologic malignancies and treatments cause abnormality in physical function and quality of life Treatments such as chemotherapy radiotherapy and hematopoietic stem cell transplantation which may have side effects on the body systems are used in early or late period The most common side effect due to chemotherapy is fatigue Vomiting weight loss anemia depression decreased aerobic capacity loss of muscle strength decreased physical functioning and deterioration in the quality of life are indirect side effects seen in patients
In the literature side effects of hematological malignancies have been investigated after treatment in patients However no study investigated exercise capacity quality of life physical activity level and pulmonary functions on newly diagnosed hematologic malignant patients Therefore the investigators aimed to compare aforementioned outcomes in newly diagnosed hematologic malignant patients and healthy controls
Detailed Description:
According to sample size calculation 30 newly diagnosed hematologic malignant patients and 30 healthy individuals will be included Before treatment submaximal exercise capacity physical activity quality of life pulmonary functions respiratory and peripheral muscle strength respiratory muscle endurance dyspnea and fatigue perception anxiety and depression will be evaluated Primary outcome measurements are exercise capacity physical activity quality of life secondary outcomes are respiratory and peripheral muscle strength respiratory muscle endurance pulmonary functions dyspnea and fatigue perception anxiety and depression
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None