Ignite Creation Date:
2024-05-05 @ 4:36 PM
Last Modification Date:
2024-10-26 @ 9:22 AM
Study NCT ID:
NCT00274183
Status:
COMPLETED
Last Update Posted:
2019-04-09
First Post:
2006-01-02
Brief Title:
Nonalcoholic Fatty Liver Disease in Taiwanese Children
Sponsor:
Far Eastern Memorial Hospital
Organization:
Far Eastern Memorial Hospital
Study Overview
Official Title:
Prevalence Clinicopathological Characteristics Biomarkers and Genetics of Nonalcoholic Steatohepatitis in Taiwanese Children
Status:
COMPLETED
Status Verified Date:
2018-12
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
Nonalcoholic fatty liver disease NAFLD is an emerging and important disease in Taiwan However the prevalence and clinical characteristics have not been studied well The purpose of this study is to resolve the aforementioned problem
Detailed Description:
Study Subjects Obesity was defined as the BMI value 95 percentile by different age- and gender groups according to the standards of the Department of Health in Taiwan
Data Collection The following data were obtained for each subject age gender BMI waist and hip circumference BMI was calculated as body weight kg height m2
In fasting venous blood samples we measured total serum bilirubin alanine aminotransferase aspartate aminotransferase γ-glutamyltransferase fasting glucose triglyceride total cholesterolhigh-density lipoprotein cholesterol insulin glucose and adiponectin
Liver Ultrasonography All participants underwent an ultrasonographic study of the liver performed by one operator
NAFLD was defined as the presence of an ultrasonographic pattern consistent with the following criteria liver-kidney echo discrepancy attenuated echo penetration and visibility of diaphragm and obscure hepatic vessel structures
Data Collection The following data were obtained for each subject age gender BMI waist and hip circumference BMI was calculated as body weight kg height m2
In fasting venous blood samples we measured total serum bilirubin alanine aminotransferase aspartate aminotransferase γ-glutamyltransferase fasting glucose triglyceride total cholesterolhigh-density lipoprotein cholesterol insulin glucose and adiponectin
Liver Ultrasonography All participants underwent an ultrasonographic study of the liver performed by one operator
NAFLD was defined as the presence of an ultrasonographic pattern consistent with the following criteria liver-kidney echo discrepancy attenuated echo penetration and visibility of diaphragm and obscure hepatic vessel structures
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None