Viewing Study NCT00005245



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Last Modification Date: 2024-10-26 @ 9:04 AM
Study NCT ID: NCT00005245
Status: COMPLETED
Last Update Posted: 2016-02-05
First Post: 2000-05-25

Brief Title: Community Structure and Cardiovascular Mortality Trends
Sponsor: University of North Carolina Chapel Hill
Organization: University of North Carolina Chapel Hill

Study Overview

Official Title: Community Structure and Cardiovascular Mortality Trends
Status: COMPLETED
Status Verified Date: 2016-02
Last Known Status: None
Delayed Posting: No
If Stopped, Why?: Not Stopped
Has Expanded Access: False
If Expanded Access, NCT#: N/A
Has Expanded Access, NCT# Status: N/A
Acronym: None
Brief Summary: To assess the relationship of community socioeconomic SE structure to cardiovascular disease and all-cause mortality trends in the United States
Detailed Description: BACKGROUND

Socioeconomic structure refers to aspects of communities -- their industries physical resources occupational and income distributions -- that create the conditions for change in health-related exposures behaviors and availability of quality medical care Preliminary studies suggest growing inequalities in ischemic heart disease mortality in communities at different levels of socioeconomic structure that probably reflect both differences in timing of onset of decline and rate of decline of mortality Despite the beginning of a national decline of ischemic heart disease mortality for white men in the middle 1960s some communities only began the decline some years later at which time the national decline accelerated Late declining communities were more likely to be nonmetropolitan and in the South Further analyses showed that the onset of decline was strongly related to measures of socioeconomic structure and that income-related characteristics could account for much of the previously observed metropolitan differential Another study showed that the decline of ischemic heart disease in both white men and women has been greater in county groups with occupational structures characterized by higher levels of white collar employment The trend toward greater relative geographic inequality of mortality appears to be stronger for ischemic heart disease than for stroke all cardiovascular disease or all-cause mortality Prevention strategies should take account of these processes not only to achieve a more equitable distribution of health but to target populations with the greatest excess risk available for reduction

DESIGN NARRATIVE

Several analyses were conducted using mortality data from the National Center for Health Statistics and population and socioeconomic data from the Census Bureau The onset of decline of ischemic heart disease in white women and Black men was analyzed in relation to geographic region metropolitan status and socioeconomic structure The association between onset of decline of ischemic heart disease and its rate of decline was studied The relationship of occupational structure and other aspects of socioeconomic structure to the rate of decline of ischemic heart disease mortality in Blacks and whites was quantified by age Geographic variations in levels and trends of stroke mortality were described in relation to socioeconomic structure The associations of socioeconomic structure cardiovascular disease risk factors blood pressure treatment and mortality were quantified in geographic areas sampled in the National Health and Nutrition Examination Survey NHANES Socioeconomic structure-mortality trend associations for ischemic heart disease and stroke were compared to associations for all cardiovascular disease all-cause and non-specific causes A detailed analysis was made of socioeconomic structure-mortality associations in the United States South with special attention to impact on Blackwhite mortality differentials

Study Oversight

Has Oversight DMC:
Is a FDA Regulated Drug?:
Is a FDA Regulated Device?:
Is an Unapproved Device?:
Is a PPSD?:
Is a US Export?:
Is an FDA AA801 Violation?:
Secondary IDs
Secondary ID Type Domain Link
R01HL042320 NIH None httpsreporternihgovquickSearchR01HL042320