Ignite Creation Date:
2024-05-05 @ 4:37 PM
Last Modification Date:
2024-10-26 @ 9:22 AM
Study NCT ID:
NCT00284219
Status:
COMPLETED
Last Update Posted:
2011-06-30
First Post:
2006-01-30
Brief Title:
High-Frequency Repetitive Transcranial Magnetic Stimulation Assists In Smoking Cessation
Sponsor:
Sheba Medical Center
Organization:
Sheba Medical Center
Study Overview
Official Title:
None
Status:
COMPLETED
Status Verified Date:
2011-06
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
Cigarette smoking is a major public health problem causing significant morbidity and mortality Yet smoking cessation therapies are often ineffective at helping smokers break their addiction
The mesolimbic dopaminergic reward system plays a crucial role in mediating the reinforcing effects of nicotine Recently acute high frequency repetitive transcranial magnetic stimulation rTMS of frontal brain regions has been shown to efficiently modulate the mesolimbic dopamine systems in both animals and humans For this reason we investigated whether 10 high-frequency 10Hz rTMS treatments over the left dorsolateral prefrontal cortex can help people to withdraw smoking in comparison to placebo rTMS
Smokers seeking to quit are recruited through newspaper advertisements Participants were randomized to 10 days of either real or placebo high frequency rTMS
The mesolimbic dopaminergic reward system plays a crucial role in mediating the reinforcing effects of nicotine Recently acute high frequency repetitive transcranial magnetic stimulation rTMS of frontal brain regions has been shown to efficiently modulate the mesolimbic dopamine systems in both animals and humans For this reason we investigated whether 10 high-frequency 10Hz rTMS treatments over the left dorsolateral prefrontal cortex can help people to withdraw smoking in comparison to placebo rTMS
Smokers seeking to quit are recruited through newspaper advertisements Participants were randomized to 10 days of either real or placebo high frequency rTMS
Detailed Description:
None
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None