Ignite Creation Date:
2024-05-05 @ 4:37 PM
Last Modification Date:
2024-10-26 @ 9:22 AM
Study NCT ID:
NCT00281112
Status:
COMPLETED
Last Update Posted:
2016-07-12
First Post:
2006-01-20
Brief Title:
Center for Reducing Asthma Disparities - HowardHopkins Centers
Sponsor:
National Heart Lung and Blood Institute NHLBI
Organization:
National Heart Lung and Blood Institute NHLBI
Study Overview
Official Title:
None
Status:
COMPLETED
Status Verified Date:
2008-07
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
To evaluate asthma morbidity in low-income African-American children and adults with asthma
Detailed Description:
BACKGROUND
Asthma is a serious chronic condition affecting over 14 million Americans but the prevalence rates are higher in certain populations eg 10 percent in inner-cities and 30 percent among the homeless vs 5 percent in a general population of whites African Americans and Hispanics from the Northeast are twice as likely to die from asthma as whites African Americans are four times as likely to be hospitalized for asthma and are five times more likely than whites to seek care for asthma at an emergency department Reasons for these higher rates are not certain and most likely result from an interaction of risk factors such as environmental exposures genetic predisposition access to appropriate medical care socioeconomic status and cultural health practices The National Heart Lung and Blood Institute supports a variety of activities to address the pressing public health problems posed by asthma However progress in reducing disparities has been disappointingly slow Separate independent research projects have generated important clues for understanding the nature and scope of the problem A more coordinated interdisciplinary and comprehensive approach to research is needed to take advantage of these clues move the science further and faster and increase our capacity to improve health outcomes among minority and economically disadvantaged populations Cooperative centers of research that foster partnerships among minority medical centers research intensive institutions and the communities in which asthma patients live will promote such advancement
The Request for Applications for the Centers for Reducing Asthma Disparities was released in October 2001 The objective of the program is to promote partnerships called Centers between a minority serving institution MSI that may not have a strong research program and a research intensive institution RII that has a track record of NIH-supported research and patient care The purpose of the partnership is to conduct collaborative research on asthma disparities ie greater prevalence of asthma higher rates of morbidity due to asthma and lesser access or use of quality medical care among minorities and poor
DESIGN NARRATIVE
The center has four research projects designed to collaboratively investigate factors associated with the disproportionate burden of asthma experienced by inner-city African-American children and adults This includes studies that will evaluate both the underlying genetic factors that may contribute to the observed excess risk in African-American communities as well as studies of provider-patient communication designed to assess intervention strategies for remediating this risk In addition an essential goal of the HowardHopkins Center for Reducing Asthma Disparities will be to create a culturally sensitive training environment that is truly reciprocal and designed to both enrich and enhance the research potential and asthma management capabilities of both participating institutions
Research project 1 will create and validate a culturally sensitive and simple to administer Asthma Communication Instrument for use in describing asthma symptoms Research project 2 will develop a tripartite communication mechanism between the patient the patient care provider and an asthma counselor Research project 3 deals with the genetics of cockroach allergy Research project 4 will develop a complementary mouse model to address the role of the genetics of cockroach sensitization as it pertains to asthma disparities
The study completion date listed in this record was obtained from the End Date entered in the Protocol Registration and Results System PRS record
Asthma is a serious chronic condition affecting over 14 million Americans but the prevalence rates are higher in certain populations eg 10 percent in inner-cities and 30 percent among the homeless vs 5 percent in a general population of whites African Americans and Hispanics from the Northeast are twice as likely to die from asthma as whites African Americans are four times as likely to be hospitalized for asthma and are five times more likely than whites to seek care for asthma at an emergency department Reasons for these higher rates are not certain and most likely result from an interaction of risk factors such as environmental exposures genetic predisposition access to appropriate medical care socioeconomic status and cultural health practices The National Heart Lung and Blood Institute supports a variety of activities to address the pressing public health problems posed by asthma However progress in reducing disparities has been disappointingly slow Separate independent research projects have generated important clues for understanding the nature and scope of the problem A more coordinated interdisciplinary and comprehensive approach to research is needed to take advantage of these clues move the science further and faster and increase our capacity to improve health outcomes among minority and economically disadvantaged populations Cooperative centers of research that foster partnerships among minority medical centers research intensive institutions and the communities in which asthma patients live will promote such advancement
The Request for Applications for the Centers for Reducing Asthma Disparities was released in October 2001 The objective of the program is to promote partnerships called Centers between a minority serving institution MSI that may not have a strong research program and a research intensive institution RII that has a track record of NIH-supported research and patient care The purpose of the partnership is to conduct collaborative research on asthma disparities ie greater prevalence of asthma higher rates of morbidity due to asthma and lesser access or use of quality medical care among minorities and poor
DESIGN NARRATIVE
The center has four research projects designed to collaboratively investigate factors associated with the disproportionate burden of asthma experienced by inner-city African-American children and adults This includes studies that will evaluate both the underlying genetic factors that may contribute to the observed excess risk in African-American communities as well as studies of provider-patient communication designed to assess intervention strategies for remediating this risk In addition an essential goal of the HowardHopkins Center for Reducing Asthma Disparities will be to create a culturally sensitive training environment that is truly reciprocal and designed to both enrich and enhance the research potential and asthma management capabilities of both participating institutions
Research project 1 will create and validate a culturally sensitive and simple to administer Asthma Communication Instrument for use in describing asthma symptoms Research project 2 will develop a tripartite communication mechanism between the patient the patient care provider and an asthma counselor Research project 3 deals with the genetics of cockroach allergy Research project 4 will develop a complementary mouse model to address the role of the genetics of cockroach sensitization as it pertains to asthma disparities
The study completion date listed in this record was obtained from the End Date entered in the Protocol Registration and Results System PRS record
Study Oversight
Has Oversight DMC:
Is a FDA Regulated Drug?:
Is a FDA Regulated Device?:
Is an Unapproved Device?:
Is a PPSD?:
Is a US Export?:
Is an FDA AA801 Violation?:
Secondary IDs
| Secondary ID | Type | Domain | Link |
|---|---|---|---|
| U01HL072433-04 | NIH | None | httpsreporternihgovquickSearchU01HL072433-04 |