Ignite Creation Date:
2024-05-05 @ 4:38 PM
Last Modification Date:
2024-10-26 @ 9:22 AM
Study NCT ID:
NCT00286663
Status:
TERMINATED
Last Update Posted:
2008-07-09
First Post:
2006-02-01
Brief Title:
Autoimmune Hepatitis Study
Sponsor:
University of Rochester
Organization:
University of Rochester
Study Overview
Official Title:
Evaluation of the Cellular Immune Response in Patients With Anti-SLALP- or Anti-LKM-Positive Autoimmune Hepatitis
Status:
TERMINATED
Status Verified Date:
2008-07
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Principal Investigator moving out of state no other staff to lead research
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
The purpose of the study is to determine the role special antibodies play in possibly identifying Autoimmune Hepatitis through the following
Identify the response of specific T cells to antibodies and Monitor the response of the cells that regulate the immune system
Identify the response of specific T cells to antibodies and Monitor the response of the cells that regulate the immune system
Detailed Description:
The object of this protocol is to characterize and monitor auto antigen-specific T cell responses in blood and liver biopsies of patients with anti-SLALP or anti-LKM-positive autoimmune hepatitis The results will provide insight into the pathogenesis of autoimmune hepatitis and the monitoring of auto antigen-specific T cell reactivity in correlation to disease exacerbation and therapy
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None