Ignite Creation Date:
2024-05-05 @ 4:38 PM
Last Modification Date:
2024-10-26 @ 9:22 AM
Study NCT ID:
NCT00285441
Status:
UNKNOWN
Last Update Posted:
2006-02-28
First Post:
2006-01-31
Brief Title:
Identification of Cytokine Profiles and T Cell Subsets Among Immunosuppressed Patients at Risk of Developing Active Tuberculosis
Sponsor:
Hvidovre University Hospital
Organization:
Hvidovre University Hospital
Study Overview
Official Title:
None
Status:
UNKNOWN
Status Verified Date:
2005-12
Last Known Status:
RECRUITING
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
The purpose of this study is to identify differences in TB specific immune responses among immunosuppressed patients latently infected with TB and patients with active TB
Detailed Description:
Immunosuppressed patients latently infected with TB are at higher risk of developing active TB than patients with normal immune functions Especially two patient categories are at risk HIV positives and patients receiving TNF-a blocking medication Existing methods of diagnosis and surveillance of latent TB infection can not identify who will develop active TB and who can control the infection There is a need for better understanding of TB specific immune functionsas we believe deficient TB specific immune reactions is a key in reactivation of latent TB infection
In this study we follow groups of latent TB infected patients with either rheumatoid arthritis or HIV We follow the patients during treatment with TNF-a blocking medication HAART treatment or prophylactic TB medication Results are correlated to patients with active TB latent TB and healthy controls
In this study we follow groups of latent TB infected patients with either rheumatoid arthritis or HIV We follow the patients during treatment with TNF-a blocking medication HAART treatment or prophylactic TB medication Results are correlated to patients with active TB latent TB and healthy controls
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None