Ignite Creation Date:
2024-05-05 @ 4:38 PM
Last Modification Date:
2024-10-26 @ 9:22 AM
Study NCT ID:
NCT00284505
Status:
COMPLETED
Last Update Posted:
2008-12-05
First Post:
2006-01-30
Brief Title:
Use of Thalidomide in Patients With Arachnoiditis
Sponsor:
Washington University School of Medicine
Organization:
Washington University School of Medicine
Study Overview
Official Title:
Prospective Study of the Use of Thalidomide in Patients With Arachnoiditis
Status:
COMPLETED
Status Verified Date:
2008-12
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
No
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
This pilot study will evaluate whether thalidomide decreases pain in patients with arachnoiditis
Detailed Description:
Arachnoiditis a neuropathic disease caused by inflamation of the arachnoid membrane that surrounds and protects the spinal nervescan result in a debilitating state that is characterized by numbing and tingling stinging and burning in the lower back or legs and possible muscle cramps twitching and spasms Current treatments are not always effective in treating the pain associated with arachnoiditis Recent research has indicated that a group of chemicals called cytokines that are produced by various cells in the body may be responsible for generating the pain response Medications that effect the release of cytokines or block the action of cytokines may reduce the pain response Various anti-cytokine medications are now being used to treat painful disease states such as rheumotoid arthritis and Crohns Disease In this study the anti-cytokine medication Thalidomide is being evaluated for its effect in treating pain associated with arachnoiditis
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None