Ignite Creation Date:
2025-12-24 @ 4:31 PM
Ignite Modification Date:
2025-12-27 @ 6:58 AM
Study NCT ID:
NCT00959166
Status:
COMPLETED
Last Update Posted:
2019-10-22
First Post:
2009-08-13
Is NOT Gene Therapy:
True
Has Adverse Events:
True
Brief Title:
To Assess Neuroinflammation and Neurocognitive Function in Patients With Acute Hepatitis C and Chronic HIV Co-Infection
Sponsor:
Imperial College London
Organization:
Study Overview
Official Title:
A Prospective Case-control Study to Assess Neuroinflammation and Neurocognitive Function in Patients With Acute Hepatitis C and Chronic HIV Co-infection - a PET Study
Status:
COMPLETED
Status Verified Date:
2019-10
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
This study plans to evaluate what happens to the brain in patients with HIV and early hepatitis C. The investigators will be comparing 3 groups of individuals:
* Group 1: Individuals with HIV infection and acute (early) hepatitis C infection
* Group 2: Individuals with HIV infection
* Group 3: Healthy volunteers
* Group 1: Individuals with HIV infection and acute (early) hepatitis C infection
* Group 2: Individuals with HIV infection
* Group 3: Healthy volunteers
Detailed Description:
Subtle changes to the brain, which doctors find difficult to detect through conversation or examination, may occur in patients with HIV and/or hepatitis C infection. It is not currently known whether the brain is affected in early (or acute) hepatitis C.
Individuals wishing to take part will complete a series of tests assessing different aspects of their brain including:
* 2 brain scans using different technology:
* Magnetic resonance imaging (MRI) brain scan with spectroscopy
* CT PET brain scan
* A computer game test which measures brain function
* 2 short questionnaires
Results of these tests will be analyzed and compared between 3 groups.
Individuals wishing to take part will complete a series of tests assessing different aspects of their brain including:
* 2 brain scans using different technology:
* Magnetic resonance imaging (MRI) brain scan with spectroscopy
* CT PET brain scan
* A computer game test which measures brain function
* 2 short questionnaires
Results of these tests will be analyzed and compared between 3 groups.
Study Oversight
Has Oversight DMC:
False
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?: