Ignite Creation Date:
2024-05-05 @ 11:07 AM
Last Modification Date:
2024-10-26 @ 9:02 AM
Study NCT ID:
NCT00001363
Status:
COMPLETED
Last Update Posted:
2008-03-04
First Post:
1999-11-03
Brief Title:
PET Scan to Map the Areas of the Brain Involved in Planning
Sponsor:
National Institute of Neurological Disorders and Stroke NINDS
Organization:
National Institutes of Health Clinical Center CC
Study Overview
Official Title:
Functional Brain Mapping of Planning Activities With 015 Water PET Blood Flow Technique
Status:
COMPLETED
Status Verified Date:
2000-05
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
Positron Emission Tomography PET is a technique used to investigate the functional activity of the brain The PET technique allows doctors to study the normal processes of the brain central nervous system of normal individuals and patients with neurologic illnesses without physical structural damage to the brain
When a region of the brain is active it uses more fuel in the form of oxygen and sugar glucose As the brain uses more fuel it produces more waste products carbon dioxide and water Blood carries fuel to the brain and waste products away from the brain As brain activity increases blood flow to and from the area of activity increases also Knowing these facts researchers can use radioactive water H215O and PET scans to observe what areas of the brain are receiving more blood flow
This study will attempt to determine the areas of the brain activated by planning processes and decision making Researchers will ask patients to participate in tests and games chess that will stimulate the areas of the brain involved with decision making and planning while undergoing the water PET blood flow technique
When a region of the brain is active it uses more fuel in the form of oxygen and sugar glucose As the brain uses more fuel it produces more waste products carbon dioxide and water Blood carries fuel to the brain and waste products away from the brain As brain activity increases blood flow to and from the area of activity increases also Knowing these facts researchers can use radioactive water H215O and PET scans to observe what areas of the brain are receiving more blood flow
This study will attempt to determine the areas of the brain activated by planning processes and decision making Researchers will ask patients to participate in tests and games chess that will stimulate the areas of the brain involved with decision making and planning while undergoing the water PET blood flow technique
Detailed Description:
This protocol will attempt to determine the topographical distribution in the brain of the cognitive components of planning using the 150 water PET blood flow technique We will administer perception motor simple decision and planning tasks using the game of chess and the Tower of Hanoi Test as paradigms Utilizing a subtraction technique we hope to identify those areas of cerebral cortex which are most activated by planning processes It is predicted that the dorsolateral frontal areas will be most prominently activated It is also predicted that the essential components of the planning process will be the same regardless of the type of plans being executed The data we collect will be of value in determining 1 the neural representation of planning processes and 2 in guiding cognitive models of the planning system
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None
Secondary IDs
| Secondary ID | Type | Domain | Link |
|---|---|---|---|
| 93-N-0077 | None | None | None |