Ignite Creation Date:
2024-05-05 @ 4:41 PM
Last Modification Date:
2024-10-26 @ 9:23 AM
Study NCT ID:
NCT00295048
Status:
COMPLETED
Last Update Posted:
2021-07-21
First Post:
2006-02-19
Brief Title:
Cognitive Remediation for Schizophrenia
Sponsor:
University of Maryland Baltimore
Organization:
University of Maryland Baltimore
Study Overview
Official Title:
Cognitive Remediation for Schizophrenia
Status:
COMPLETED
Status Verified Date:
2021-07
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
The purpose of this study is to evaluate the efficacy of an innovative computer driven cognitive rehabilitation program for individuals with schizophrenia and related disorders
Detailed Description:
Schizophrenia is associated with neurocognitive impairment diminished life satisfaction lack of independence and poor functioning in social occupational and other desired and expected community roles The personal social and economic costs of this illness are enormous Neurocognitive deficits eg slowed thinking poor attention and memory inadequate problem solving are now recognized as core features of the illness and primary contributors to functional impairment among patients Bellack Gold Buchanan 1999 Green 1996 While standard antipsychotic medications improve psychotic symptomatology in many patients their impact on neurocognition is modest at best and dramatic functional deficits remain even after adequate pharmacological treatment Keefe et al 1999 Hence there is growing interest in alternative treatment strategies to address cognitive deficits including computer-assisted cognitive remediation
The purpose of this project is to assess the efficacy of a computer-assisted cognitive remediation program we have developed Computer Assisted Cognitive Remediation CACR Fifty individuals with schizophrenia and related disorders will be recruited and randomly assigned to one of two conditions a 36 sessions of CACR or b 36 sessions of a manualized computer control condition RC The efficacy of CACR will be assessed on behavioral performance in three dimensions 1 on the trained learning exercises 2 on neuropsychological measures and 3 on role play based assessments of everyday problem solving We hypothesize that CACR will be more effective than the control treatment in each domain
The purpose of this project is to assess the efficacy of a computer-assisted cognitive remediation program we have developed Computer Assisted Cognitive Remediation CACR Fifty individuals with schizophrenia and related disorders will be recruited and randomly assigned to one of two conditions a 36 sessions of CACR or b 36 sessions of a manualized computer control condition RC The efficacy of CACR will be assessed on behavioral performance in three dimensions 1 on the trained learning exercises 2 on neuropsychological measures and 3 on role play based assessments of everyday problem solving We hypothesize that CACR will be more effective than the control treatment in each domain
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None