Ignite Creation Date:
2024-05-06 @ 11:03 AM
Last Modification Date:
2024-10-26 @ 12:40 PM
Study NCT ID:
NCT03426488
Status:
RECRUITING
Last Update Posted:
2018-02-08
First Post:
2017-12-18
Brief Title:
Northern Sweden Health and Disease Study
Sponsor:
Umeå University
Organization:
Umeå University
Study Overview
Official Title:
Northern Sweden Health and Disease Study
Status:
RECRUITING
Status Verified Date:
2017-12
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
NSHDS
Brief Summary:
NSHDS Northern Sweden Health and Disease Study is an umbrella term for a prospective biobank with related survey data The sample collection consists of three subcohorts Västerbotten Intervention Programme VIP Mammography Screening Project MA and MONICA MONItoring of Trends and Determinants in CArdiovascular Disease The blood samples are stored at the Northern Sweden Biobank
Detailed Description:
The overall aim of the NSHDS is to support frontline research with particular emphasis on improving diagnostic tools for clinical use as well as finding early markers of disease using the blood samples tissue and associated health data from the NSHDS Furthermore basic research regarding risk factors as well as pathogenetic pathways are promoted
The prospective blood samples and related survey data can be linked to national registries for health outcomes such as cancer diagnosis for which there is a near 100 completeness of the data
VIP - VÄSTERBOTTEN INTERVENTION PROGRAMME The VIP is a long-term project intended for health promotion of the population of the county of Västerbotten approximately 254000 inhabitants All individuals 40 50 and 60 years of age in the county are invited for screening They are asked to complete a questionnaire concerning various lifestyle factors including diet and to donate a blood sample to be frozen for later research purposes The cohort is population-based and the inclusion of individuals started 1985 and is ongoing The participation rate has ranged between 48 and 67 of the population But a large number has not been invited for screening Among those invited the participation rate has been very high The material is population based
The blood samples consist primarily of EDTA ethylenediaminetetraacetic acid and heparin blood samples divided into plasma erythrocyte concentrate and buffy coat Questionnaire data are linked to blood samples
The majority of samples are fasting samples Number of individuals 103100 Individuals with repeated samples 43500 Sampling occasions 151200 October 2016
MA - MAMMOGRAPHY SCREENING PROJECT
Samples and data are collected in connection with mammography screenings 1995-2006 The blood samples consist primarily of EDTA and heparin blood samples divided into plasma erythrocyte concentrate and buffy coat and for a certain percentage the DNA is also extracted The cohort consists of women 18-82 years old 95 between 48 and 70 years old
Survey data can be linked to the blood samples
Individuals 28800 Individuals with repeated samples 14600 Sampling occasions 54000
THE MONICA STUDY
The MONICA study is a longitudinal population-based database for research in cardiovascular disease and diabetes Since 1985 seven screenings has been performed 1986 1990 1994 1999 2004 2009 and 2014 of a randomized selection of the population in the counties of Västerbotten and Norrbotten in Northern Sweden
Individuals 11800 Individuals with repeated samples 3500 Sampling occasions 15300
This registration will only cover blood sampling screenings since 1990 and dietary data optional MONICA study screenings since 1986 as a part of the National Environmental Biobank The participation rates have been 69-81
A separate registration is expected for the basic MONICA study
The prospective blood samples and related survey data can be linked to national registries for health outcomes such as cancer diagnosis for which there is a near 100 completeness of the data
VIP - VÄSTERBOTTEN INTERVENTION PROGRAMME The VIP is a long-term project intended for health promotion of the population of the county of Västerbotten approximately 254000 inhabitants All individuals 40 50 and 60 years of age in the county are invited for screening They are asked to complete a questionnaire concerning various lifestyle factors including diet and to donate a blood sample to be frozen for later research purposes The cohort is population-based and the inclusion of individuals started 1985 and is ongoing The participation rate has ranged between 48 and 67 of the population But a large number has not been invited for screening Among those invited the participation rate has been very high The material is population based
The blood samples consist primarily of EDTA ethylenediaminetetraacetic acid and heparin blood samples divided into plasma erythrocyte concentrate and buffy coat Questionnaire data are linked to blood samples
The majority of samples are fasting samples Number of individuals 103100 Individuals with repeated samples 43500 Sampling occasions 151200 October 2016
MA - MAMMOGRAPHY SCREENING PROJECT
Samples and data are collected in connection with mammography screenings 1995-2006 The blood samples consist primarily of EDTA and heparin blood samples divided into plasma erythrocyte concentrate and buffy coat and for a certain percentage the DNA is also extracted The cohort consists of women 18-82 years old 95 between 48 and 70 years old
Survey data can be linked to the blood samples
Individuals 28800 Individuals with repeated samples 14600 Sampling occasions 54000
THE MONICA STUDY
The MONICA study is a longitudinal population-based database for research in cardiovascular disease and diabetes Since 1985 seven screenings has been performed 1986 1990 1994 1999 2004 2009 and 2014 of a randomized selection of the population in the counties of Västerbotten and Norrbotten in Northern Sweden
Individuals 11800 Individuals with repeated samples 3500 Sampling occasions 15300
This registration will only cover blood sampling screenings since 1990 and dietary data optional MONICA study screenings since 1986 as a part of the National Environmental Biobank The participation rates have been 69-81
A separate registration is expected for the basic MONICA study
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None