Ignite Creation Date:
2024-05-06 @ 11:17 AM
Last Modification Date:
2024-10-26 @ 12:43 PM
Study NCT ID:
NCT03483233
Status:
COMPLETED
Last Update Posted:
2022-03-02
First Post:
2018-03-07
Brief Title:
Neural Bases of the Check Process
Sponsor:
Hospices Civils de Lyon
Organization:
Hospices Civils de Lyon
Study Overview
Official Title:
Neural Bases of the Check Process
Status:
COMPLETED
Status Verified Date:
2022-02
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
Check
Brief Summary:
Effective exploration of the environment check for information to improve ones own performance are fundamental abilities of human cognition These abilities are dependent on the process of cognitive control
However they are clearly impaired and uncontrollable in certain behavioral disorders such as obsessive-compulsive disorder OCD Compulsive checks of these patients spontaneously associated with a feeling of intense uncertainty suggest disturbances of evaluative and metacognitive functions However no biological observations have yet been able to feed these hypotheses
The evaluation of decisions and actions involves the middle cingulate cortex MCC which belongs to a cortico-subcortical network structurally and functionally altered in OCD patients Cingulotomy has long been used as a therapy in severe OCD with However the precise part of the cingulate cortex that contributes to check and its pathological forms remains to be discovered
The purpose of this research campaign is to determine through functional magnetic resonance imaging fMRI and electroencephalography EEG in healthy human subjects
1 the location and role of the MCC region involved in normal check decision processes
2 determine the identity of the entire network involved
However they are clearly impaired and uncontrollable in certain behavioral disorders such as obsessive-compulsive disorder OCD Compulsive checks of these patients spontaneously associated with a feeling of intense uncertainty suggest disturbances of evaluative and metacognitive functions However no biological observations have yet been able to feed these hypotheses
The evaluation of decisions and actions involves the middle cingulate cortex MCC which belongs to a cortico-subcortical network structurally and functionally altered in OCD patients Cingulotomy has long been used as a therapy in severe OCD with However the precise part of the cingulate cortex that contributes to check and its pathological forms remains to be discovered
The purpose of this research campaign is to determine through functional magnetic resonance imaging fMRI and electroencephalography EEG in healthy human subjects
1 the location and role of the MCC region involved in normal check decision processes
2 determine the identity of the entire network involved
Detailed Description:
None
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None
Secondary IDs
| Secondary ID | Type | Domain | Link |
|---|---|---|---|
| 2018-A00405-50 | OTHER | ID-RCB | None |