Ignite Creation Date:
2024-05-06 @ 11:20 AM
Last Modification Date:
2024-10-26 @ 12:43 PM
Study NCT ID:
NCT03490474
Status:
COMPLETED
Last Update Posted:
2018-12-13
First Post:
2018-03-21
Brief Title:
Pain Modulatory Profiles in Massage for Healthy Participants
Sponsor:
University of Florida
Organization:
University of Florida
Study Overview
Official Title:
Pain Modulatory Profiles in Massage for Healthy Participants
Status:
COMPLETED
Status Verified Date:
2018-12
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
One in ten adults experience widespread pain Neck pain for example is a prevalent condition with a high rate of recurrence that affects between 104 and 213 of the population annually
Massage is a common manual therapy intervention for individuals with musculoskeletal pain However the mechanisms of massage are not well established Also the conditioned pain modulation CPM paradigm is a dynamic quantitative sensory testing measure of a pain inhibitory process in which pain sensitivity is lessened in response to a remotely applied painful stimulus
This study will evaluate the association between pain inducing massage and the conditioned pain modulation paradigm
Massage is a common manual therapy intervention for individuals with musculoskeletal pain However the mechanisms of massage are not well established Also the conditioned pain modulation CPM paradigm is a dynamic quantitative sensory testing measure of a pain inhibitory process in which pain sensitivity is lessened in response to a remotely applied painful stimulus
This study will evaluate the association between pain inducing massage and the conditioned pain modulation paradigm
Detailed Description:
Conditioned pain modulation CPM is the physical manifestation of the diffuse noxious inhibitory control DNIC an endogenous pain inhibitory pathway in which pain inhibits pain Conditioned pain modulation is less efficient in individuals with chronic pain conditions and it is a predictor for the development of chronic pain
Massage is a common manual therapy intervention for individuals with musculoskeletal pain Greater changes in pain sensitivity occur following pain inducing massage suggesting a mechanism dependent upon the efficiency of the conditioned pain modulation response
The study team will evaluate the association between pain inducing massage and the conditioned pain modulation paradigm Healthy participants will be randomly assigned to receive a pain inducing massage a pain free massage or participate in a coldpressor task Pre-and post intervention pain sensitivity including conditioned pain modulation will be assessed The study team will determine if analgesia induced by massage is similar to the conditioned pain modulation paradigm and compare changes in pain sensitivity between groups
Previous research has indicated pain inducing massage is more effective than pain free massage suggesting a mechanism dependent upon conditioned pain modulation However this study will be the first to systematically investigate if analgesia induced by pain inducing massage is similar to the conditioned pain modulation paradigm Furthermore this study will be the first to determine the association between baseline conditioned pain modulation and massage related hypoalgesia
Massage is a common manual therapy intervention for individuals with musculoskeletal pain Greater changes in pain sensitivity occur following pain inducing massage suggesting a mechanism dependent upon the efficiency of the conditioned pain modulation response
The study team will evaluate the association between pain inducing massage and the conditioned pain modulation paradigm Healthy participants will be randomly assigned to receive a pain inducing massage a pain free massage or participate in a coldpressor task Pre-and post intervention pain sensitivity including conditioned pain modulation will be assessed The study team will determine if analgesia induced by massage is similar to the conditioned pain modulation paradigm and compare changes in pain sensitivity between groups
Previous research has indicated pain inducing massage is more effective than pain free massage suggesting a mechanism dependent upon conditioned pain modulation However this study will be the first to systematically investigate if analgesia induced by pain inducing massage is similar to the conditioned pain modulation paradigm Furthermore this study will be the first to determine the association between baseline conditioned pain modulation and massage related hypoalgesia
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None