Ignite Creation Date:
2024-05-05 @ 4:43 PM
Last Modification Date:
2024-10-26 @ 9:23 AM
Study NCT ID:
NCT00306124
Status:
UNKNOWN
Last Update Posted:
2007-10-25
First Post:
2006-03-21
Brief Title:
Dopaminergic Enhancement of Learning and Memory in Healthy Adults and Patients With DementiaMild Cognitive Impairment
Sponsor:
University Hospital Muenster
Organization:
University Hospital Muenster
Study Overview
Official Title:
Dopaminergic Enhancement of Learning and Memory LL_001 Project on DementiaMCI
Status:
UNKNOWN
Status Verified Date:
2007-10
Last Known Status:
RECRUITING
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
This study aims to determine whether levodopa is effective in boosting learning and memory in healthy subjects and patients with dementia or Mild Cognitive Impairment
We also examine in healthy subjects using functional magnetic resonance imaging which brain regions mediate improved learning after levodopa administration
We also examine in healthy subjects using functional magnetic resonance imaging which brain regions mediate improved learning after levodopa administration
Detailed Description:
Prior work of our group shows that the dopamine precursor levodopa markedly improves word learning success in healthy subjects In this randomized placebo-controlled double-blind trial we probe whether administration of levodopa improves learning performance as compared to placebo administration on neuropsychological tests and in an associative learning paradigm We postulate that levodopa improves learning success and memory performance in healthy subjects while the effect in patients with dementia or Mild Cognitive Impairment might depend on other factors including severity of memory impairment
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None