Ignite Creation Date:
2024-05-05 @ 11:07 AM
Last Modification Date:
2024-10-26 @ 9:02 AM
Study NCT ID:
NCT00001288
Status:
COMPLETED
Last Update Posted:
2008-03-04
First Post:
1999-11-03
Brief Title:
Brain Blood Flow Studies of Language and Memory
Sponsor:
National Institute of Neurological Disorders and Stroke NINDS
Organization:
National Institutes of Health Clinical Center CC
Study Overview
Official Title:
Cerebral Blood Flow Studies of Language and Memory
Status:
COMPLETED
Status Verified Date:
2003-06
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
Positron Emission Tomography PET is a technique used to investigate the functional activity of the brain The PET technique allows doctors to study the normal processes of the brain central nervous system of normal individuals and patients with neurologic illnesses without physical structural damage to the brain
When a region of the brain is active it uses more fuel in the form of oxygen and sugar glucose As the brain uses more fuel it produces more waste products carbon dioxide and water Blood carries fuel to the brain and waste products away from the brain As brain activity increases blood flow to and from the area of activity increases also Knowing these facts researchers can use radioactive water H215O and PET scans to observe what areas of the brain are receiving more blood flow
This study is designed to use positron emission tomography PET with radioactive water H215O to determine the areas of the brain associated with memory and language Patients participating in the study will be made up of normal volunteers patients with epilepsy and patients with other abnormalities related to the surface of the brain non-epileptic focal cortical dysfunctions
When a region of the brain is active it uses more fuel in the form of oxygen and sugar glucose As the brain uses more fuel it produces more waste products carbon dioxide and water Blood carries fuel to the brain and waste products away from the brain As brain activity increases blood flow to and from the area of activity increases also Knowing these facts researchers can use radioactive water H215O and PET scans to observe what areas of the brain are receiving more blood flow
This study is designed to use positron emission tomography PET with radioactive water H215O to determine the areas of the brain associated with memory and language Patients participating in the study will be made up of normal volunteers patients with epilepsy and patients with other abnormalities related to the surface of the brain non-epileptic focal cortical dysfunctions
Detailed Description:
This protocol will use positron emission tomography PET with H2015 and functional MRI to examine localization of memory and language in normal control subjects and patients with localization-related epilepsy
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None
Secondary IDs
| Secondary ID | Type | Domain | Link |
|---|---|---|---|
| 91-N-0134 | None | None | None |