Ignite Creation Date:
2024-05-05 @ 4:44 PM
Last Modification Date:
2024-10-26 @ 9:23 AM
Study NCT ID:
NCT00304421
Status:
COMPLETED
Last Update Posted:
2007-09-17
First Post:
2006-03-16
Brief Title:
Comparison of the Nighttime Effects of Two Different Drugs on Subjects With GERD
Sponsor:
VA Greater Los Angeles Healthcare System
Organization:
VA Greater Los Angeles Healthcare System
Study Overview
Official Title:
Comparison of the Nighttime Effects of Rabeprazole 20 mg to Pantoprazole 40 mg on Standard Meal Stimulated Gastric Acid Secretion and Intragastric pH in H Pylori Negative Volunteer Subjects With GERD
Status:
COMPLETED
Status Verified Date:
2007-09
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
The purpose of the study is to compare the effect of two different drugs rabeprazole 20 mg and pantoprazole 40 mg and their effects on the amount of acid produced by your stomach on evening and at night after standard protein meal
Detailed Description:
Gastric acid secretion can be divided into two phases the daytime phase and the nocturnal phase Nocturnal acid reflux is presumably more damaging because of loss of salivary neutralization The present study is designed to measure effects of rabeprazole and pantoprazole on post-prandial and nocturnal gastric acid secretion and intragastric pH in H pylori-negative volunteers with gastroesophageal reflux disease These measurement will be used to compare the degree of inhibition of gastric acid secretion between the two drugs
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None