Ignite Creation Date:
2024-05-05 @ 11:07 AM
Last Modification Date:
2024-10-26 @ 9:02 AM
Study NCT ID:
NCT00001836
Status:
COMPLETED
Last Update Posted:
2008-03-04
First Post:
1999-11-03
Brief Title:
Detection of Coronary Artery Calcification Comparison of Volumetric and Electron Beam Computed Tomography
Sponsor:
National Institutes of Health Clinical Center CC
Organization:
National Institutes of Health Clinical Center CC
Study Overview
Official Title:
Detection of Coronary Artery Calcification Comparison of Volumetric and Electron Beam Computed Tomography
Status:
COMPLETED
Status Verified Date:
2001-11
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
Electron beam computed tomography EBCT has been regarded as the state-of-the-art investigation for detecting and quantitating coronary artery calcification However EBCT is expensive and the asymmetric gantry geometry makes it less useful for routine scanning thus EBCT is not readily available to the general population Recent reports have shown that volumetric also known as helical or spiral scanners which are much more commonly available than EBCT can detect coronary artery calcifications Updated software available to the NIH which will allow for EKG gating of volumetric scans should improve the quality of the images and thus improve the ability to accurately quantitate coronary calcification by volumetric scanners We would like to compare the results of volumetric scans with that of standard EBCT in order to characterize similarities and differences between the two scanning techniques We propose to obtain EBCT and volumetric CT scans of the coronary arteries in a group of patients with known or suspected coronary artery disease and to calculate the calcium score by each method Our primary analysis will be a comparison of the sensitivities of the two methods
Detailed Description:
Electron beam computed tomography EBCT has been regarded as the state-of-the-art investigation for detecting and quantitating coronary artery calcification However EBCT is expensive and the asymmetric gantry geometry makes it less useful for routine scanning thus EBCT is not readily available to the general population Recent reports have shown that volumetric also known as helical or spiral scanners which are much more commonly available than EBCT can detect coronary artery calcifications Updated software available to the NIH which will allow for EKG gating of volumetric scans should improve the quality of the images and thus improve the ability to accurately quantitate coronary calcification by volumetric scanners We would like to compare the results of volumetric scans with that of standard EBCT in order to characterize similarities and differences between the two scanning techniques We propose to obtain EBCT and volumetric CT scans of the coronary arteries in a group of patients with known or suspected coronary artery calcification including subjects of sufficiently advanced age and to calculate the calcium score by each method Our primary analysis will be a comparison of the sensitivities of the two methods
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None
Secondary IDs
| Secondary ID | Type | Domain | Link |
|---|---|---|---|
| 99-CC-0001 | None | None | None |