Ignite Creation Date:
2024-05-05 @ 9:36 AM
Last Modification Date:
2024-10-26 @ 9:04 AM
Study NCT ID:
NCT00005297
Status:
COMPLETED
Last Update Posted:
2016-02-29
First Post:
2000-05-25
Brief Title:
Age-related Prevalence of Sleep Respiratory Disturbances
Sponsor:
National Heart Lung and Blood Institute NHLBI
Organization:
National Heart Lung and Blood Institute NHLBI
Study Overview
Official Title:
None
Status:
COMPLETED
Status Verified Date:
2005-03
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
To determine the prevalence and longitudinal course of sleep apnea among men and women and to examine the associations of apnea oxygen desaturation snoring high blood pressure and other biomedical correlates
Detailed Description:
BACKGROUND
Sleep apnea is characterized by repetitive cessations of respiration during sleep with consequent decreases in arterial oxygen saturation Sleep apnea can be caused by upper airway obstruction or by central nervous system failure to sufficiently excite the diaphragm and accessory respiratory muscles However in most cases both processes are involved Hypopneas in which airflow is significantly compromised without complete cessations of respiratory flow and snoring are often found in association with apneas Both apneas and hypopneas cause repetitive disruptions of sleep consequent daytime somnolence and complex cardio-respiratory disturbances
DESIGN NARRATIVE
The study was longitudinal in design A stratified random sample of adults in San Diego was used to examine risk factors in the prevalence of sleep respiratory disturbances A structured random sample was selected by random digit telephone dialing Subjects were studied in their homes Some were followed yearly during the project Each volunteer gave a brief sleep history and medical review including blood pressure measurement the National Interview Survey And Quality of Well-being Scale Blood oxygen saturation pulse rate snoring and sleep duration were recorded for three nights State-of-the-art computerized pulse oximeters and microprocessor-based activitylight monitors were used Subjects found to have the most severe sleep respiratory disturbances underwent laboratory polysomnograms to add descriptive data and to validate the survey methodology The prevalence of respiratory disturbances in sleep was analyzed as a function of age and sex Associations with several aspects of morbidity were determined The longitudinal course of respiratory disturbances in sleep were examined
The study completion date listed in this record was obtained from the End Date entered in the Protocol Registration and Results System PRS record
Sleep apnea is characterized by repetitive cessations of respiration during sleep with consequent decreases in arterial oxygen saturation Sleep apnea can be caused by upper airway obstruction or by central nervous system failure to sufficiently excite the diaphragm and accessory respiratory muscles However in most cases both processes are involved Hypopneas in which airflow is significantly compromised without complete cessations of respiratory flow and snoring are often found in association with apneas Both apneas and hypopneas cause repetitive disruptions of sleep consequent daytime somnolence and complex cardio-respiratory disturbances
DESIGN NARRATIVE
The study was longitudinal in design A stratified random sample of adults in San Diego was used to examine risk factors in the prevalence of sleep respiratory disturbances A structured random sample was selected by random digit telephone dialing Subjects were studied in their homes Some were followed yearly during the project Each volunteer gave a brief sleep history and medical review including blood pressure measurement the National Interview Survey And Quality of Well-being Scale Blood oxygen saturation pulse rate snoring and sleep duration were recorded for three nights State-of-the-art computerized pulse oximeters and microprocessor-based activitylight monitors were used Subjects found to have the most severe sleep respiratory disturbances underwent laboratory polysomnograms to add descriptive data and to validate the survey methodology The prevalence of respiratory disturbances in sleep was analyzed as a function of age and sex Associations with several aspects of morbidity were determined The longitudinal course of respiratory disturbances in sleep were examined
The study completion date listed in this record was obtained from the End Date entered in the Protocol Registration and Results System PRS record
Study Oversight
Has Oversight DMC:
Is a FDA Regulated Drug?:
Is a FDA Regulated Device?:
Is an Unapproved Device?:
Is a PPSD?:
Is a US Export?:
Is an FDA AA801 Violation?:
Secondary IDs
| Secondary ID | Type | Domain | Link |
|---|---|---|---|
| R01HL040930 | NIH | None | httpsreporternihgovquickSearchR01HL040930 |