Ignite Creation Date:
2024-05-05 @ 11:07 AM
Last Modification Date:
2024-10-26 @ 9:05 AM
Study NCT ID:
NCT00006432
Status:
COMPLETED
Last Update Posted:
2007-06-25
First Post:
2000-11-03
Brief Title:
Acute Glycemic Effects of a Very Low Fat Diet in Type 2 Diabetes
Sponsor:
National Center for Research Resources NCRR
Organization:
National Center for Research Resources NCRR
Study Overview
Official Title:
None
Status:
COMPLETED
Status Verified Date:
2007-06
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
There is some consensus that high fat diets can contribute to the development of obesity and type 2 diabetes in humans and animals An increase in dietary fat has been shown to produce obesity and diabetes in mice such diet-induced diabetes can be reversed by reducing the fat in the diet In humans there is some evidence that low-fat diets can produce acute improvements in blood sugar control in type 2 diabetes-even in the absence of weight loss In most human studies however dietary fat reduction has been accompanied by a reduction in total calorie intake It is thus not possible to separate the effects of these 2 metabolic changes The purpose of this study is to gather preliminary information on the effect of a very-low-fat diet on blood metabolism in persons with type 2 diabetes The design incorporates controlled feeding procedures and 30 men and women with type 2 diabetes will be given all foods for 4 weeks--a 2-week diet standardization period diet composition 35 fat 15 protein 50 carbohydrate followed by a 2-week experimental diet period The experimental diet conditions are A continuation of the moderately-high-fat standardization diet or B a very-low-fat diet composed of 10 fat 15 protein 75 carbohydrate Outcomes will be measured after the standardization and the experimental periods The primary outcome variable is fasting plasma glucose secondary outcomes are fasting insulin carbohydrate meal tolerance insulin secretion and blood lipids In addition we will gather descriptive data on the potential acceptability and utility of a very-low-fat diet constructed using the fat substitute olestra sucrose polyester There are no results yet
Detailed Description:
None
Study Oversight
Has Oversight DMC:
Is a FDA Regulated Drug?:
Is a FDA Regulated Device?:
Is an Unapproved Device?:
Is a PPSD?:
Is a US Export?:
Is an FDA AA801 Violation?:
Secondary IDs
| Secondary ID | Type | Domain | Link |
|---|---|---|---|
| M01RR000030 | NIH | None | httpsreporternihgovquickSearchM01RR000030 |