Ignite Creation Date:
2024-05-05 @ 4:49 PM
Last Modification Date:
2024-10-26 @ 9:24 AM
Study NCT ID:
NCT00320684
Status:
COMPLETED
Last Update Posted:
2012-07-02
First Post:
2006-05-01
Brief Title:
Serotonin Transporter Concentrations in Women With a History of Anorexia Nervosa
Sponsor:
New York State Psychiatric Institute
Organization:
New York State Psychiatric Institute
Study Overview
Official Title:
A Positron Emission Tomography Study of the Serotonin Transporter in Weight-Restored Women With Anorexia Nervosa
Status:
COMPLETED
Status Verified Date:
2012-06
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
This study will compare the concentrations of serotonin transporter in the brains of women with a history of anorexia nervosa who are currently maintaining a normal weight to those of healthy women of normal weight
Detailed Description:
Anorexia nervosa AN is a serious eating disorder that is associated with substantial morbidity and mortality Despite being dangerously underweight people with AN believe that they are overweight and frequently exhibit symptoms of depression and anxiety Other symptoms of AN include the following resistance to maintaining a healthy body weight fear of gaining weight or becoming overweight and denial of the seriousness of ones current low body weight Relapse rates for AN are extremely high Serotonin is a neurotransmitter or chemical messenger that affects mood impulse control and appetite A serotonin transporter is a specialized protein that allows cells to communicate with each other by using serotonin Disturbances in the serotonergic system the network of nerve cells that uses serotonin as its neurotransmitter may contribute to the behaviors that are characteristic of AN This study will compare women with a history of AN who are now maintaining a normal weight to healthy women of normal weight in terms of the concentration of serotonin transporter in their brains
Participants in this observational study will undergo one positron emission tomography PET scan and one magnetic resonance imaging MRI scan Both will be used to measure the concentration of the serotonin transporter A radioactive tracer will be used for the PET scan and will be administered via an intravenous catheter line No treatment will be provided in this study
Participants in this observational study will undergo one positron emission tomography PET scan and one magnetic resonance imaging MRI scan Both will be used to measure the concentration of the serotonin transporter A radioactive tracer will be used for the PET scan and will be administered via an intravenous catheter line No treatment will be provided in this study
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None
Secondary IDs
| Secondary ID | Type | Domain | Link |
|---|---|---|---|
| DATR AK-TNNS1 | US NIH GrantContract | None | httpsreporternihgovquickSearchK23MH002021 |
| K23MH002021 | NIH | None | None |