Ignite Creation Date:
2024-05-05 @ 11:08 AM
Last Modification Date:
2024-10-26 @ 9:04 AM
Study NCT ID:
NCT00004458
Status:
TERMINATED
Last Update Posted:
2005-06-24
First Post:
1999-10-18
Brief Title:
Longitudinal and Biological Study of Childhood Disintegrative Disorder
Sponsor:
Eunice Kennedy Shriver National Institute of Child Health and Human Development NICHD
Organization:
Office of Rare Diseases ORD
Study Overview
Official Title:
None
Status:
TERMINATED
Status Verified Date:
2003-10
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
OBJECTIVES
I Compare the developmental course language acquisition diagnostic stability predictors of outcome and restricted interests and behaviors of childhood disintegrative disorder versus autism and non-autistic developmental delays
II Collect data on molecular genetics of proband and family members
I Compare the developmental course language acquisition diagnostic stability predictors of outcome and restricted interests and behaviors of childhood disintegrative disorder versus autism and non-autistic developmental delays
II Collect data on molecular genetics of proband and family members
Detailed Description:
PROTOCOL OUTLINE
Patients are evaluated with the following questionnaires at ages 2-3 years and again at ages 5-9 The Autism Diagnostic Interview ADI The Autism Diagnostic Observation Schedule ADOS Assessment of cognitive functioning Expressive and receptive language Adaptive functioning Measures of burden and functional assessment The Aberrant Behavior Checklist The Connors Rating Scale - Parent and Teacher version and Autism Behavior Checklist
An MRI and EEG are performed and blood samples are collected from patients and family members for molecular genetic studies
Patients are evaluated with the following questionnaires at ages 2-3 years and again at ages 5-9 The Autism Diagnostic Interview ADI The Autism Diagnostic Observation Schedule ADOS Assessment of cognitive functioning Expressive and receptive language Adaptive functioning Measures of burden and functional assessment The Aberrant Behavior Checklist The Connors Rating Scale - Parent and Teacher version and Autism Behavior Checklist
An MRI and EEG are performed and blood samples are collected from patients and family members for molecular genetic studies
Study Oversight
Has Oversight DMC:
Is a FDA Regulated Drug?:
Is a FDA Regulated Device?:
Is an Unapproved Device?:
Is a PPSD?:
Is a US Export?:
Is an FDA AA801 Violation?:
Secondary IDs
| Secondary ID | Type | Domain | Link |
|---|---|---|---|
| YALE-HIC-5895 | None | None | None |
| YALE-5P01HD0300830 | None | None | None |