Ignite Creation Date:
2024-05-05 @ 4:51 PM
Last Modification Date:
2024-10-26 @ 9:24 AM
Study NCT ID:
NCT00320177
Status:
COMPLETED
Last Update Posted:
2019-12-12
First Post:
2006-04-29
Brief Title:
Eating Behavior in Children
Sponsor:
Eunice Kennedy Shriver National Institute of Child Health and Human Development NICHD
Organization:
National Institutes of Health Clinical Center CC
Study Overview
Official Title:
Eating Behavior in Children
Status:
COMPLETED
Status Verified Date:
2014-10-28
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
This study will explore the eating habits of children and determine if eating behavior is linked to genetics
Children between 8 and 17 years of age may be eligible for this study It will include children who have experienced loss of control over eating children who report overeating without loss of control and children who report experiencing neither of the above Candidates will be screened with the following
Medical history and brief physical examination including height weight and body fat measurements Body fat is measured using a device called a Bod Pod The child sits inside the device for about 5 minutes and the machine determines body fat by measuring air movement The child must wear a tight-fitting swimsuit for this test
Urine test to look for sugar or protein in the urine and to test for pregnancy in females
Blood tests for routine chemistries and for gene studies related to eating behaviors
Questionnaires and interviews about the childs general health and eating habits
Acclimatization to test meal conditions for the study The child is given a yogurt shake to drink and fills out rating scales before and after the drink
Participants will come to the Clinical Center two times at 830 am for laboratory meal testing At each visit the child will do the following
In the morning eat a breakfast of apple juice and a buttered English muffin
Between 10 am and 2 pm pursue activities at the Clinical Center recreation facility or the NIH classroom but may not eat or drink anything that contains calories
At 2 pm fill out rating scales about his or her hunger level
At 230 pm eat from a food buffet that will be made available
After eating repeat rating scales about hunger level
The procedure for both visits will be the same except at one visit the child will be instructed to eat as much as you would eat at a normal meal and at the other visit the instruction will be to let yourself go and eat as much as you want
Children between 8 and 17 years of age may be eligible for this study It will include children who have experienced loss of control over eating children who report overeating without loss of control and children who report experiencing neither of the above Candidates will be screened with the following
Medical history and brief physical examination including height weight and body fat measurements Body fat is measured using a device called a Bod Pod The child sits inside the device for about 5 minutes and the machine determines body fat by measuring air movement The child must wear a tight-fitting swimsuit for this test
Urine test to look for sugar or protein in the urine and to test for pregnancy in females
Blood tests for routine chemistries and for gene studies related to eating behaviors
Questionnaires and interviews about the childs general health and eating habits
Acclimatization to test meal conditions for the study The child is given a yogurt shake to drink and fills out rating scales before and after the drink
Participants will come to the Clinical Center two times at 830 am for laboratory meal testing At each visit the child will do the following
In the morning eat a breakfast of apple juice and a buttered English muffin
Between 10 am and 2 pm pursue activities at the Clinical Center recreation facility or the NIH classroom but may not eat or drink anything that contains calories
At 2 pm fill out rating scales about his or her hunger level
At 230 pm eat from a food buffet that will be made available
After eating repeat rating scales about hunger level
The procedure for both visits will be the same except at one visit the child will be instructed to eat as much as you would eat at a normal meal and at the other visit the instruction will be to let yourself go and eat as much as you want
Detailed Description:
Little is known about the eating habits of children under laboratory conditions In this exploratory study we aim to examine the relationships between measured food intake during meals binge eating behaviors as assessed by interview and polymorphisms in genes believed to be involved in the regulation of energy intake We will study children who report they have experienced loss of control over eating children who report overeating without loss of control and children who report neither of these episodes and assess the impact of two different meal instructions on their eating behavior We will ask children to eat a meal in the laboratory setting on two occasions The only difference between the two meals will be a pre-meal instruction Participants will be asked either to eat normally the normal meal instruction or to let yourself go the binge meal instruction Participants will be assessed for affective state degree of hunger fullness and desire to binge presence of overeating or loss of control eating attitudes and dieting and general school and social adjustment Participants DNA will be sequenced to seek polymorphisms in genes relevant for appetite such as the leptin and melanocortin 4 receptor genes to examine whether genetic variation in the leptin signaling pathway can account for variation in reported or actual eating behaviors Samples will also be obtained for hormones believed to be relevant for food intake By accurately describing eating behavior in children in relation to their age weight history of dieting andor overeating behavior and genetic variation we can refine current theoretical models of disordered eating
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None
Secondary IDs
| Secondary ID | Type | Domain | Link |
|---|---|---|---|
| 04-CH-0050 | None | None | None |