Viewing Study NCT00339378



Ignite Creation Date: 2024-05-05 @ 4:52 PM
Last Modification Date: 2024-10-26 @ 9:25 AM
Study NCT ID: NCT00339378
Status: COMPLETED
Last Update Posted: 2017-07-02
First Post: 2006-06-19

Brief Title: Incidence and Mortality of Childhood Cancer Among Children of Farmer Pesticide Applications
Sponsor: National Institute of Environmental Health Sciences NIEHS
Organization: National Institutes of Health Clinical Center CC

Study Overview

Official Title: Incidence and Mortality of Childhood Cancer Among Children of Farmer Pesticide Applicators
Status: COMPLETED
Status Verified Date: 2007-06-11
Last Known Status: None
Delayed Posting: No
If Stopped, Why?: Not Stopped
Has Expanded Access: False
If Expanded Access, NCT#: N/A
Has Expanded Access, NCT# Status: N/A
Acronym: None
Brief Summary: Previous studies have estabished pesticide exposure as a possible risk factor for childhood cancer The Agricultural Health Study AHS a prospective cohort study of pesticide exposure among 51000 pesticide applicators in North Carolina and Iowa provides an opportunity to study childhood cancer incidence and mortality among the children of pesticide applicators Name and dates of birth for 21985 children were previously provided by adult participants in the AHS The current study seeks to identify cases of cancer among these children through record linkage to state cancer and death registries Cancer incidence and mortality within the cohort will be compared with national data through standardized incidence and mortality ratios A limited case-cohort comparison of pesticide exposures will also be performed Approximately 44 cases of childhood cancer are expected to be identified No follow-up or contact with cases is anticipated It is anticipated that the study results will provide insight into the relationship of pesticide and other farm exposures to the pathogenesis of childhood cancer
Detailed Description: Previous studies have estabished pesticide exposure as a possible risk factor for childhood cancer The Agricultural Health Study AHS a prospective cohort study of pesticide exposure among 51000 pesticide applicators in North Carolina and Iowa provides an opportunity to study childhood cancer incidence and mortality among the children of pesticide applicators Name and dates of birth for 21985 children were previously provided by adult participants in the AHS The current study seeks to identify cases of cancer among these children through record linkage to state cancer and death registries Cancer incidence and mortality within the cohort will be compared with national data through standardized incidence and mortality ratios A limited case-cohort comparison of pesticide exposures will also be performed Approximately 44 cases of childhood cancer are expected to be identified No follow-up or contact with cases is anticipated It is anticipated that the study results will provide insight into the relationship of pesticide and other farm exposures to the pathogenesis of childhood cancer

Study Oversight

Has Oversight DMC: None
Is a FDA Regulated Drug?: None
Is a FDA Regulated Device?: None
Is an Unapproved Device?: None
Is a PPSD?: None
Is a US Export?: None
Is an FDA AA801 Violation?: None
Secondary IDs
Secondary ID Type Domain Link
OH00-E-N025 None None None