Ignite Creation Date:
2024-05-05 @ 4:53 PM
Last Modification Date:
2024-10-26 @ 9:25 AM
Study NCT ID:
NCT00339560
Status:
COMPLETED
Last Update Posted:
2020-06-16
First Post:
2006-06-19
Brief Title:
A Population-Based Case-Control Study of Biliary Tract Cancers in Shanghai China
Sponsor:
National Cancer Institute NCI
Organization:
National Institutes of Health Clinical Center CC
Study Overview
Official Title:
A Population-Based Case-Control Study of Biliary Tract Cancers in Shanghai China
Status:
COMPLETED
Status Verified Date:
2020-06
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
The key aims of this study include estimation of possible risk associated with a history of gallstones bacterial infection for the biliary tract other medical history diet use of tobacco and alcohol obesity reproductive factors and family history of cancer Information will be used to examine risk patterns a seperately by anatomic subsite b among patients with gallbladder cancer vs controls undergoing cholecystectomy for gallstones c among the patients with bile duct cancer vs Hospital controls without cancer who undergo surgery for removal of bile duct stones We will also attempt to ascertain reasons for cancer who undergo surgery for removal of bile duct stones We will also attempt to ascertain reasons for the rising incidence of biliary tract cancers in Shanghai Serum collected from all subjects will be analyzed for estrogens and other hormones vitamins C and E cholesterol and bacterial antibodies including salmonella typhi paratyphi and escherischia coli Bile fluid will be cultured for aerobic bacteria and gallstones analyzed for color cholesterol and evidence of bacteria infection A major challenge in biliary tract cancer research is to determine how cancer risk factors differ from those for gallstones or biliary duct stone disease since many people have gallstones or biliary duct stones but few develop cancer
Detailed Description:
The key aims of this study include estimation of possible risk associated with a history of gallstones bacterial infection for the biliary tract other medical history diet use of tobacco and alcohol obesity reproductive factors and family history of cancer Information will be used to examine risk patterns a seperately by anatomic subsite b among patients with gallbladder cancer vs controls undergoing cholecystectomy for gallstones c among the patients with bile duct cancer vs Hospital controls without cancer who undergo surgery for removal of bile duct stones We will also attempt to ascertain reasons for cancer who undergo surgery for removal of bile duct stones We will also attempt to ascertain reasons for the rising incidence of biliary tract cancers in Shanghai Serum collected from all subjects will be analyzed for estrogens and other hormones vitamins C and E cholesterol and bacterial antibodies including salmonella typhi paratyphi and escherischia coli Bile fluid will be cultured for aerobic bacteria and gallstones analyzed for color cholesterol and evidence of bacteria infection A major challenge in biliary tract cancer research is to determine how cancer risk factors differ from those for gallstones or biliary duct stone disease since many people have gallstones or biliary duct stones but few develop cancer
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None
Secondary IDs
| Secondary ID | Type | Domain | Link |
|---|---|---|---|
| OH97-C-N028 | None | None | None |