Ignite Creation Date:
2024-05-05 @ 4:53 PM
Last Modification Date:
2024-10-26 @ 9:25 AM
Study NCT ID:
NCT00338156
Status:
COMPLETED
Last Update Posted:
2015-07-28
First Post:
2006-06-16
Brief Title:
Observational Study of the Remodelling Process Following Myocardial Infarct
Sponsor:
Helse Stavanger HF
Organization:
Helse Stavanger HF
Study Overview
Official Title:
Assessment of the Relationship Between Collagen Turnover Left Ventricular Remodelling and Myocardial Scarring Assessed by Cardiac Magnetic Resonance and Neurohumoral Activation in Patients With Previous Myocardial Infarction
Status:
COMPLETED
Status Verified Date:
2010-07
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
This study will assess the relationship between collagen turnover neurohormonal activation scarring and left ventricle remodelling in patients 3 years following a myocardial infarction
Detailed Description:
A multinational trial compared losartan vs captopril in 5477 postinfarction patients with symptoms of heart failure andor evidence of left ventricular dysfunction The trial was terminated in 2002 and the results of the main trial have been published In this trial a collagen and neurohumoral substudy was performed to assess the importance of collagen turnover in this population A total of 235 patients were included from 18 centres Blood was taken at randomisation 1 month 1 year and 2 years
The present study will recruit surviving patients among the 119 individuals that were randomised to the neurohumoral substudy at the Stavanger University Hospital The study will assess the relationship between collagen turnover neurohormonal activation scarring and left ventricle remodelling in these patients about 3 years following the index myocardial infarction
The data collected at the 3-year follow-up visit will be compared to data from the initial study
The present study will recruit surviving patients among the 119 individuals that were randomised to the neurohumoral substudy at the Stavanger University Hospital The study will assess the relationship between collagen turnover neurohormonal activation scarring and left ventricle remodelling in these patients about 3 years following the index myocardial infarction
The data collected at the 3-year follow-up visit will be compared to data from the initial study
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None
Secondary IDs
| Secondary ID | Type | Domain | Link |
|---|---|---|---|
| Helse Vest 911017 | OTHER_GRANT | Helse Vest RHF | None |