Ignite Creation Date:
2024-05-05 @ 4:53 PM
Last Modification Date:
2024-10-26 @ 9:25 AM
Study NCT ID:
NCT00336739
Status:
COMPLETED
Last Update Posted:
2007-07-23
First Post:
2006-06-12
Brief Title:
The Effect of Cinacalcet on Gastric Acid Output in Healthy Subjects
Sponsor:
Tufts University
Organization:
Tufts University
Study Overview
Official Title:
None
Status:
COMPLETED
Status Verified Date:
2007-06
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
The purpose of this study is to determine whether cinacalcet will increase gastric acid secretion in healthy volunteers
Detailed Description:
The calcium sensing receptor CaSR was originally found on parathyroid and renal cells and more recently it has been identified on cells that regulate gastric acid secretion G cells and parietal cells However its role in regulating acid secretion in humans is completely unknown and is of potential importance because an acid environment in the stomach enhances intestinal calcium absorption In this pilot project we will stimulate the CaSR with a CaSR-agonist called cinacalcet Our hypothesis is that activation of the CaSR will in turn increase gastric acid production in healthy volunteers
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None