Ignite Creation Date:
2024-05-05 @ 4:55 PM
Last Modification Date:
2024-10-26 @ 9:26 AM
Study NCT ID:
NCT00347035
Status:
TERMINATED
Last Update Posted:
2006-10-26
First Post:
2006-06-30
Brief Title:
INFLUENCE OF TOPICAL INDOMETHACIN ON HYPOTHENSIVE EFFECT OF BRIMONIDINE
Sponsor:
Federal University of São Paulo
Organization:
Federal University of São Paulo
Study Overview
Official Title:
INFLUENCE OF TOPICAL INDOMETHACIN ON HYPOTHENSIVE EFFECT OF BRIMONIDINE
Status:
TERMINATED
Status Verified Date:
2006-06
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
Purpose
To evaluate the influence of the nonsteroidal anti-inflammatory indomethacin on the brimonidine intraocular pressure IOP lowering effect
Methods
A randomized double-masked study was carried out Patients medicated with timolol maleate 05 and needed complementary medication were random allocated into two groups a brimonidine tartarate 015 and indomethacin 1 or b brimonidine tartarate and placebo balanced saline solution If patients both eyes were eligible they were allocated to the same group
IOP was measured at two weeks one month and two months after study beginning The mean IOP of the eyes was used for analyzes in the case of two eligible eyes For statistical analyzes repeated measures analysis was used
To evaluate the influence of the nonsteroidal anti-inflammatory indomethacin on the brimonidine intraocular pressure IOP lowering effect
Methods
A randomized double-masked study was carried out Patients medicated with timolol maleate 05 and needed complementary medication were random allocated into two groups a brimonidine tartarate 015 and indomethacin 1 or b brimonidine tartarate and placebo balanced saline solution If patients both eyes were eligible they were allocated to the same group
IOP was measured at two weeks one month and two months after study beginning The mean IOP of the eyes was used for analyzes in the case of two eligible eyes For statistical analyzes repeated measures analysis was used
Detailed Description:
None
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None