Ignite Creation Date:
2024-05-05 @ 11:08 AM
Last Modification Date:
2024-10-26 @ 9:05 AM
Study NCT ID:
NCT00006309
Status:
COMPLETED
Last Update Posted:
2016-02-18
First Post:
2000-09-28
Brief Title:
Pooling of Cohort Studies on Diet Coronary Disease
Sponsor:
National Heart Lung and Blood Institute NHLBI
Organization:
National Heart Lung and Blood Institute NHLBI
Study Overview
Official Title:
None
Status:
COMPLETED
Status Verified Date:
2004-12
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
To quantify the role of dietary factors in the etiology of coronary heart disease by pooling data from 10 major prospective studies on diet and coronary heart disease
Detailed Description:
DESIGN NARRATIVE
Specific hypotheses tested included an adverse effect of saturated fat and carotenoids alpha-carotene lutein and lycopene flavonoids folic acid and vitamin B6 Plausible biological interactions between nutrients such as fatty acids of the n-6 and n-3 series were also explored Each participating center sent data on tape to the coordinating unit at the Department of Nutrition Harvard School of Public Health The relations of dietary factors and coronary heart disease were first estimated within each study and compared for consistency Data were then combined to obtain the best overall estimates taking into account the validity of dietary data collected at each center Members from study centers met annually to discuss the interpretation of findings Over 6000 cases of myocardial infarction or coronary death were anticipated which should have provided excellent precision in measuring associations and allowed the comparison of extreme intakes that were poorly represented in individual studies
The study completion date listed in this record was obtained from the End Date entered in the Protocol Registration and Results System PRS record
Specific hypotheses tested included an adverse effect of saturated fat and carotenoids alpha-carotene lutein and lycopene flavonoids folic acid and vitamin B6 Plausible biological interactions between nutrients such as fatty acids of the n-6 and n-3 series were also explored Each participating center sent data on tape to the coordinating unit at the Department of Nutrition Harvard School of Public Health The relations of dietary factors and coronary heart disease were first estimated within each study and compared for consistency Data were then combined to obtain the best overall estimates taking into account the validity of dietary data collected at each center Members from study centers met annually to discuss the interpretation of findings Over 6000 cases of myocardial infarction or coronary death were anticipated which should have provided excellent precision in measuring associations and allowed the comparison of extreme intakes that were poorly represented in individual studies
The study completion date listed in this record was obtained from the End Date entered in the Protocol Registration and Results System PRS record
Study Oversight
Has Oversight DMC:
Is a FDA Regulated Drug?:
Is a FDA Regulated Device?:
Is an Unapproved Device?:
Is a PPSD?:
Is a US Export?:
Is an FDA AA801 Violation?:
Secondary IDs
| Secondary ID | Type | Domain | Link |
|---|---|---|---|
| R01HL058904 | NIH | None | httpsreporternihgovquickSearchR01HL058904 |