Ignite Creation Date:
2024-05-06 @ 1:40 PM
Last Modification Date:
2024-10-26 @ 1:18 PM
Study NCT ID:
NCT04088019
Status:
RECRUITING
Last Update Posted:
2024-02-28
First Post:
2019-09-11
Brief Title:
Proportion of Clinical Improvement Type 1 Interferon IFN Score Changes in Idiopathic Uveitis Patients With Interferon Gamma Release Assay IGRA Positive
Sponsor:
Fakultas Kedokteran Universitas Indonesia
Organization:
Fakultas Kedokteran Universitas Indonesia
Study Overview
Official Title:
Proportion of Clinical Improvement and Score Comparison of Type 1 Interferon Transcriptomic Analysis in Idiopathic Uveitis Patients With IGRA Positive Before and After Anti-Tuberculosis Drugs Treatment Cohort Prospective Study
Status:
RECRUITING
Status Verified Date:
2024-02
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
The aim of this study is to determine the proportion of clinical improvement the score changing of type 1 interferon selected gene expression and analysis of transcriptomics profiling in patients with idiopathic uveitis positive IGRA before and after receiving Anti-Tuberculosis Therapy ATT
Hopefully by conducting this research we are able to provide valid data that demonstrate the advantagesdisadvantages usage of Anti-Tuberculosis Therapy in patients with idiopathic uveitis IGRA positive that correlate with type I IFN This research is a part of our efforts in discovering bio-marker candidates of idiopathic uveitis IGRA positive clinical patients who will benefit from the ATT administration
Hopefully by conducting this research we are able to provide valid data that demonstrate the advantagesdisadvantages usage of Anti-Tuberculosis Therapy in patients with idiopathic uveitis IGRA positive that correlate with type I IFN This research is a part of our efforts in discovering bio-marker candidates of idiopathic uveitis IGRA positive clinical patients who will benefit from the ATT administration
Detailed Description:
Diagnostic of Idiopathic Uveitis IGRA Positive patients were still unclear This situation happens because it is still cant be explained if the uveitis from the patients was caused by mycobacterium tuberculosis or not which leads to doubtfulness for Anti-Tuberculosis Treatment ATT This study aims to help to provide evidence on whether ATT usage for Idiopathic Uveitis IGRA Positive would bring beneficial impact for the patients This study will try to analyze the data from clinical improvements Type 1 Interferon changes and transcriptomics analysis from the patients
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None