Ignite Creation Date:
2024-05-05 @ 4:59 PM
Last Modification Date:
2024-10-26 @ 9:27 AM
Study NCT ID:
NCT00367354
Status:
TERMINATED
Last Update Posted:
2014-12-09
First Post:
2006-08-18
Brief Title:
Respiratory Motion Analysis in Children With MRI
Sponsor:
Emory University
Organization:
Emory University
Study Overview
Official Title:
Respiratory Motion Analysis in Children for Improvement of MR Magnetic Resonance Imaging of Congenital Heart Disease
Status:
TERMINATED
Status Verified Date:
2014-12
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Lack of funding
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
The purpose of this project is to analyze the respiratory motion process as relevant in cardiac MRI imaging and apply the results for development of improved imaging methods and software correction To accomplish this we will develop an imaging protocol for monitoring respiratory motion
The imaging protocol will be limited to less than five minutes of acquisition time so it may be performed as piggyback acquisition following clinically prescribed imaging studies on pediatric and adult cardiac MRI patients but will also be applied to normal healthy volunteers
Hypothesis Characterization of respiratory motion will help improve image quality by allowing optimized scan acquisition and retrospective correction of acquired data
The imaging protocol will be limited to less than five minutes of acquisition time so it may be performed as piggyback acquisition following clinically prescribed imaging studies on pediatric and adult cardiac MRI patients but will also be applied to normal healthy volunteers
Hypothesis Characterization of respiratory motion will help improve image quality by allowing optimized scan acquisition and retrospective correction of acquired data
Detailed Description:
Cardiac magnetic resonance imaging MRI is used heavily in the research setting but its use is limited in clinical practice the main reason being artifact noise from respiratory and cardiac motion To counteract these sources of motion many different applications have been applied For cardiac motion ECG electrocardiogram gating is widely used while respiratory motion reduction uses methods of breath holding or respiratory gating techniques
Patients will be recruited based on whether they are a normal healthy volunteer or a patient already receiving a routine cardiac MRI
Normal Healthy Volunteers Patients will be recruited via a flyer posted in various locations at Emory University The contents of this flyer will adhere strictly to Emory IRB Advertisement guidelines Subjects will register by contacting Marijn Brunner PhD by email or telephone
Patients already scheduled for a routine cardiac MRI The MRI technical specialist will review the laboratory schedule daily Those who are already scheduled for a routine cardiac MRI will be approached by a study staff member in the Childrens MRI Department The patient will be asked if heshe would wish to enroll in this study The patient will be requested to sign a consent prior to any study procedures being performed
MRI image data will be collected by the prescribed protocol for respiratory monitoring All MRI data will be acquired by standard FDA approved imaging methods The image data will be transferred by network to the Pediatrics Imaging Research Laboratory where they will be stored on a password-protected computer and analyzed
Patients will be recruited based on whether they are a normal healthy volunteer or a patient already receiving a routine cardiac MRI
Normal Healthy Volunteers Patients will be recruited via a flyer posted in various locations at Emory University The contents of this flyer will adhere strictly to Emory IRB Advertisement guidelines Subjects will register by contacting Marijn Brunner PhD by email or telephone
Patients already scheduled for a routine cardiac MRI The MRI technical specialist will review the laboratory schedule daily Those who are already scheduled for a routine cardiac MRI will be approached by a study staff member in the Childrens MRI Department The patient will be asked if heshe would wish to enroll in this study The patient will be requested to sign a consent prior to any study procedures being performed
MRI image data will be collected by the prescribed protocol for respiratory monitoring All MRI data will be acquired by standard FDA approved imaging methods The image data will be transferred by network to the Pediatrics Imaging Research Laboratory where they will be stored on a password-protected computer and analyzed
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None