Ignite Creation Date:
2024-05-05 @ 5:01 PM
Last Modification Date:
2024-10-26 @ 9:26 AM
Study NCT ID:
NCT00362778
Status:
COMPLETED
Last Update Posted:
2012-03-20
First Post:
2006-08-08
Brief Title:
Intensive Insulin Therapy in Non-diabetic Patients With Acute Myocardial Infarction and Hyperglycaemia
Sponsor:
Hospital Clinic of Barcelona
Organization:
Hospital Clinic of Barcelona
Study Overview
Official Title:
Intensive Insulin Therapy in Non-diabetic Patients With Acute Myocardial Infarction and Hyperglycaemia
Status:
COMPLETED
Status Verified Date:
2012-03
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
INSUCOR
Brief Summary:
Hyperglycemia at admission has been associated with bad prognosis in patients with acute myocardial infarction AMI The clinical benefit of intensive treatment with insulin has been evaluated in diabetic patients admitted to intensive care units The aim of our study was to assess the short-term effects and the safety of strict glycemic control in subjects with AMI and hyperglycemia without a previous history of diabetes
Detailed Description:
Twenty-eight non-previously diabetic patients admitted with AMI and hyperglycemia were randomized to two treatment arms administered during the first 48 hours the intensive group n13 received intravenous insulin with target glycemia levels of 80-110mgdL while the conventional group n15 received subcutaneous insulin only when glycemia was ³ 160mgdL High-sensitivity C-reactive protein HS-CRP was determined at 48 hours and before discharge and an oral glucose tolerance test OGTT was performed at 1 month
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None