Ignite Creation Date:
2024-05-05 @ 5:01 PM
Last Modification Date:
2024-10-26 @ 9:27 AM
Study NCT ID:
NCT00379301
Status:
COMPLETED
Last Update Posted:
2012-06-14
First Post:
2006-09-20
Brief Title:
Efficacy of Different Ablation Strategies for Controlling Atrial Fibrillation
Sponsor:
University of Pennsylvania
Organization:
University of Pennsylvania
Study Overview
Official Title:
Efficacy of Different Ablation Strategies in Achieving Long-Term Arrhythmia Control in Patients With Persistent or Permanent Atrial Fibrillation
Status:
COMPLETED
Status Verified Date:
2012-06
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
RASTA
Brief Summary:
This study involves treatment for atrial fibrillation AF-the most common heart condition in the US-where the upper chambers of the heart beat very fast and in a disorganized manner This can be felt as palpitations tiredness shortness of breath and passing out plus can lead to stroke damage to the heart muscle and a shorter life span Study participants will receive a common treatment for atrial fibrillation called radiofrequency ablation RFA where small lesions or burns are made inside the heart to cut off the abnormal impulses that cause AF The purpose of this study is to compare the effectiveness of three different common ablation strategies in patients with persistent or permanent AF Subjects will be randomized like drawing straws to be treated with one of the three strategies to see if there is a difference in how well atrial fibrillation is controlled after treatment
Detailed Description:
In most cases AF originates where the pulmonary veins PV enter the left upper chamber of the heart known as the left atrium LA Common to the procedure in each arm of the study is pulmonary vein isolation PVI or ablation of tissue around the pulmonary vein entrances After PVI the procedure continues with ablation in other areas of the LA where similar abnormal impulses are found The three strategies for continuing with ablation after PVI are described in the Arms section below
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None