Ignite Creation Date:
2024-05-06 @ 2:03 PM
Last Modification Date:
2024-10-26 @ 1:24 PM
Study NCT ID:
NCT04206033
Status:
COMPLETED
Last Update Posted:
2021-07-27
First Post:
2019-12-18
Brief Title:
Hemophilia and Bone Metabolism Study of Monocytic Populations and Inflammatory Proteins
Sponsor:
Nantes University Hospital
Organization:
Nantes University Hospital
Study Overview
Official Title:
Hemophilia and Bone Metabolism Study of Monocytic Populations and Inflammatory Proteins
Status:
COMPLETED
Status Verified Date:
2021-07
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
BOHEM
Brief Summary:
The investigators propose as part of the study to carry out for each patient
An analysis of monocytic populations by flow cytometry CD14 CD16 CD45 CD68 CD115 CCR2 CX3CR1 CD163 and CD206
A population assessment of Myeloid-Derived Suppressor Cells MDSC
Assays of cytokines and chemokines involved in inflammation by multiplex analyzes Il-1 α and β Il-4 Il-6 Il-10 Il-13 TNF- α TGF- β CRP leptin IFN- β
Specialized dosages of proteins involved in bone metabolism RANKL osteoprotegerin M-CSF TRAPCP5
An analysis of monocytic populations by flow cytometry CD14 CD16 CD45 CD68 CD115 CCR2 CX3CR1 CD163 and CD206
A population assessment of Myeloid-Derived Suppressor Cells MDSC
Assays of cytokines and chemokines involved in inflammation by multiplex analyzes Il-1 α and β Il-4 Il-6 Il-10 Il-13 TNF- α TGF- β CRP leptin IFN- β
Specialized dosages of proteins involved in bone metabolism RANKL osteoprotegerin M-CSF TRAPCP5
Detailed Description:
None
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None