Ignite Creation Date:
2024-05-05 @ 5:04 PM
Last Modification Date:
2024-10-26 @ 9:28 AM
Study NCT ID:
NCT00387062
Status:
COMPLETED
Last Update Posted:
2008-06-24
First Post:
2006-10-10
Brief Title:
Computer-Based Training in Patients With Post-Chemotherapy Cognitive Impairment
Sponsor:
Posit Science Corporation
Organization:
Posit Science Corporation
Study Overview
Official Title:
Computer-Based Training in Patients With Post-Chemotherapy Cognitive Impairment A Pilot Study
Status:
COMPLETED
Status Verified Date:
2008-06
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
The investigators hypothesize that continuous active interaction with environments that are demanding to sensory cognitive and motor systems together with imbedded rewards for successful performance will help improve memory and cognitive functioning in patients suffering from chemobrain
Detailed Description:
Breast cancer is the most common malignancy in women in the United States with an estimated 211240 new cases of invasive breast cancer diagnosed among women and 1700 diagnosed in men in 2005 While cure rates have improved significantly chemotherapy for breast cancer is associated with a number of negative side effects One of which is a deficit in cognitive function a condition commonly referred to as chemobrain While the debate about cognitive decline being a result of chemotherapy is still ongoing there is clear evidence of cognitive decline in women with breast cancer post-chemotherapy Cognitive decline is often reported to affect memory attention executive functioning and information processing speed
Studies suggest that incidence of chemobrain ranges from 17 - 75 in women who have undergone chemotherapyThis cognitive impairment affects quality of life by impacting patients ability to concentrate make decisions and to fulfill family career and community responsibilities
Although there is uncertainty about the mechanisms that can lead to this cognitive decline there is a pressing need to identify interventions that will alleviate its symptoms and help breast cancer survivors recover their cognitive functioning and resume their roles and activities at the pre-cancer level
Brain plasticity refers to the brains capacity for physical and functional change it is this capacity that explains how experience induces learning throughout life On the basis of a growing body of literature in the fields of psychophysics neurology neuropsychology and brain plasticity we hypothesize that the brain processing machinery can be refined elaborated and strengthened through rigorous training and learning The purpose of this study is to investigate if such training can improve cognitive functioning
We hypothesize that continuous active interaction with environments that are demanding to sensory cognitive and motor systems together with imbedded rewards for successful performance will help improve memory and cognitive functioning in patients suffering from chemobrain
Studies suggest that incidence of chemobrain ranges from 17 - 75 in women who have undergone chemotherapyThis cognitive impairment affects quality of life by impacting patients ability to concentrate make decisions and to fulfill family career and community responsibilities
Although there is uncertainty about the mechanisms that can lead to this cognitive decline there is a pressing need to identify interventions that will alleviate its symptoms and help breast cancer survivors recover their cognitive functioning and resume their roles and activities at the pre-cancer level
Brain plasticity refers to the brains capacity for physical and functional change it is this capacity that explains how experience induces learning throughout life On the basis of a growing body of literature in the fields of psychophysics neurology neuropsychology and brain plasticity we hypothesize that the brain processing machinery can be refined elaborated and strengthened through rigorous training and learning The purpose of this study is to investigate if such training can improve cognitive functioning
We hypothesize that continuous active interaction with environments that are demanding to sensory cognitive and motor systems together with imbedded rewards for successful performance will help improve memory and cognitive functioning in patients suffering from chemobrain
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None