Ignite Creation Date:
2025-12-24 @ 5:24 PM
Ignite Modification Date:
2025-12-25 @ 2:58 PM
Study NCT ID:
NCT05177250
Status:
UNKNOWN
Last Update Posted:
2022-07-27
First Post:
2021-12-09
Is NOT Gene Therapy:
False
Has Adverse Events:
False
Brief Title:
Association of Bisphenol A,Paraben Exposure and Type 2 Diabetes
Sponsor:
Cairo University
Organization:
Study Overview
Official Title:
The Possible Association Between Bisphenol A, Paraben Exposure and Type 2 Diabetic Adult Patients.
Status:
UNKNOWN
Status Verified Date:
2022-07
Last Known Status:
RECRUITING
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
The aim of this study is to evaluate the association between BPA , paraben levels and type 2 DM patients
Detailed Description:
The first phase of the study will include a questionnaire :
* The cases and control will be asked about demographic information such as residence, age, education, and occupation.
* History of discovery of diabetes.
* Exposure to products and materials such as polycarbonate plastics, cosmetics and beverages containing bisphenol A and paraben and it will be evaluated through exposure sheet through asking about dietary exposure, Environmental exposure and medical exposure.
Then clinical evaluation including:
* Full clinical examination will be performed for cases and control.
* Anthropological data:
their weights, heights and waist circumference will be measured. The body mass index (BMI) will be calculated by weight (kg)/height (m)2 formula.
* Investigations: routine and specific investigation as blood glucose level, HbA1c and lipid profile.
* Urine specimens will be collected in clean, glass containers will labeled with the subject identification number. Turbid sample or those containing blood will be excluded.
* All specimens will be stored frozen below 20 degree centigrade.
* Urine samples will be analyzed by High Performance liquid chromatograph (HPLC) to detect bispenol A and parabens levels.
* The cases and control will be asked about demographic information such as residence, age, education, and occupation.
* History of discovery of diabetes.
* Exposure to products and materials such as polycarbonate plastics, cosmetics and beverages containing bisphenol A and paraben and it will be evaluated through exposure sheet through asking about dietary exposure, Environmental exposure and medical exposure.
Then clinical evaluation including:
* Full clinical examination will be performed for cases and control.
* Anthropological data:
their weights, heights and waist circumference will be measured. The body mass index (BMI) will be calculated by weight (kg)/height (m)2 formula.
* Investigations: routine and specific investigation as blood glucose level, HbA1c and lipid profile.
* Urine specimens will be collected in clean, glass containers will labeled with the subject identification number. Turbid sample or those containing blood will be excluded.
* All specimens will be stored frozen below 20 degree centigrade.
* Urine samples will be analyzed by High Performance liquid chromatograph (HPLC) to detect bispenol A and parabens levels.
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?: