Viewing Study NCT00005155



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Study NCT ID: NCT00005155
Status: COMPLETED
Last Update Posted: 2016-05-13
First Post: 2000-05-25

Brief Title: Physiological and Psychosocial Correlates of Type A Behavior
Sponsor: National Heart Lung and Blood Institute NHLBI
Organization: National Heart Lung and Blood Institute NHLBI

Study Overview

Official Title: None
Status: COMPLETED
Status Verified Date: 2000-05
Last Known Status: None
Delayed Posting: No
If Stopped, Why?: Not Stopped
Has Expanded Access: False
If Expanded Access, NCT#: N/A
Has Expanded Access, NCT# Status: N/A
Acronym: None
Brief Summary: To test the physiological and psychosocial correlates of Type A behavior
Detailed Description: BACKGROUND

The Type A behavior pattern as described by Friedman and Rosenman is characterized by extremes of competitiveness easily aroused hostility a sense of urgency and aggression In 1981 the Review Panel of Coronary Prone Behavior and Coronary Heart Disease concluded that the Type A behavior pattern was associated with an increased risk for coronary heart disease Studies have challenged the independent predictive value of the behavior pattern with respect to coronary heart disease There was a need to develop physiological measurements related to coronary-prone behavior and to reexamine the stability of the psychological assessment It was hypothesized that Type A behavior or some component such as hostility might be associated with a state of chronic generalized sympathetic-adrenal arousal Preliminary research was conducted on interpersonal dynamic correlates of Type A behavior among married couples Research was needed on whether certain types of marriages according to the Type AB classification of the two spouses are more pathogenic than others Additional research is also needed on which components of the global Type A pattern were of primary importance as risk factors for coronary disease and which components were enduring which were transient and which were situationally related

In 1982 a household survey on Type A behavior was initiated Measures included the Jenkins Activity Survey the Framingham Type A Questionnaire hostility scales and other behavioral tests Information was also collected on demographic variables social support marital satisfaction life events social values and job and family stress After the household survey was completed the respondents were contacted by the Type A interviewers and the Structured Interviews conducted A total of 1114 Type A interviews were completed yielding 902 primary respondents and 239 spouses

DESIGN NARRATIVE

The concurrent relationship of the Structured Interview SI global and component Type A behavior measures were tested to levels of chronic and acute sympathetic nervous system activity as assessed by platelet and plasma catecholamines heart rate blood pressure and pupil size The correlations among heart rate pupil size blood pressure and the plasma and platelet catecholamine measures were determined as were the relationships with reported global health chronic disease and functional disability levels The five-year predictability was tested of reported global health chronic disease and functional disability from measures of global and component Type A behavior

Tests were made of the differences in the chronic and acute sympathetic-adrenal responses as assessed by platelet and plasma catecholamines pupil size heart rate and blood pressure among married couples having different combinations of Structured Interview global and component Type A classifications The five year marital stability and health of these couples were followed A comparison was made of one week test-retest reliability with the five year stability of the Structured Interview global and component Type A measures

The study completion date listed in this record was obtained from the End Date entered in the Protocol Registration and Results System PRS record

Study Oversight

Has Oversight DMC:
Is a FDA Regulated Drug?:
Is a FDA Regulated Device?:
Is an Unapproved Device?:
Is a PPSD?:
Is a US Export?:
Is an FDA AA801 Violation?:
Secondary IDs
Secondary ID Type Domain Link
R01HL028094 NIH None httpsreporternihgovquickSearchR01HL028094