Ignite Creation Date:
2024-05-05 @ 5:07 PM
Last Modification Date:
2024-10-26 @ 9:28 AM
Study NCT ID:
NCT00395005
Status:
COMPLETED
Last Update Posted:
2007-03-23
First Post:
2006-10-31
Brief Title:
Correlation of Urinary Kallikrein With Cytokines Proteinuria and Renal Function in Chronic Renal Disease Patients
Sponsor:
National Taiwan University Hospital
Organization:
National Taiwan University Hospital
Study Overview
Official Title:
The Correlation of Urine Tissue Kallikrein Protein Level With Cytokines Degree of Proteinuria and Renal Function Deterioration in Chronic Renal Disease Patients After Angiotensin II Receptor Blocking
Status:
COMPLETED
Status Verified Date:
2006-10
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
Urinary kallikrein excretion is known to increase in patients with nephrotic syndrome and sick cell disease but decrease in patients with chronic kidney disease or uremia Some of authors consider urinary kallikrein is a marker of nephropathy To evaluate the possible role of kallikrein kinin system in chronic kidney disease we conduct a retrospective longitudinal observation study Patients who participating in the Efficacy of Pentoxifylline on Chronic Kidney Disease study are included in the study The morning spot urinary kallikrein and cytokines are measured at the time point of 0 and 12 month in addition to clinical parameters The correlation of urinary kallikrein and cytokine concentration will be evaluated Using multiple regression model the relationship of urinary kallikrein excretion with degree of proteinuria creatinine clearance and other clinical parameter will also be evaluated
Detailed Description:
None
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None